Date published: 2026-2-4

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2-Phenylbutyric Acid (CAS 90-27-7)

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Alternate Names:
α-Ethylphenylacetic acid; (±)-2-Phenylbutyric acid
CAS Number:
90-27-7
Molecular Weight:
164.20
Molecular Formula:
C10H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Phenylbutyric Acid is an organic compound that is utilized in diverse research areas including organic synthesis and materials science. Its structure, which features a phenyl group attached to a four-carbon butyric acid chain, makes it an interesting candidate for the study of aromatic compound properties and their interactions with biological systems. In synthetic chemistry, 2-Phenylbutyric Acid serves as a precursor for the synthesis of a variety of esters and amides, which are valuable for understanding reaction mechanisms and developing new synthetic routes. Additionally, this compound is used in the design of liquid crystals and other advanced materials due to its ability to contribute to the desired physical properties such as thermal stability and phase transition behaviors. Research on 2-Phenylbutyric Acid is also pertinent in the field of supramolecular chemistry, where it may be involved in the formation of self-assembled structures and the exploration of molecular recognition processes.


2-Phenylbutyric Acid (CAS 90-27-7) References

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  2. Preparative Enantioseparation of β-Substituted-2-Phenylpropionic Acids by Countercurrent Chromatography With Substituted β-Cyclodextrin as Chiral Selectors.  |  Tong, S., et al. 2015. Chirality. 27: 795-801. PMID: 26333843
  3. Analytical Enantioseparation of β-Substituted-2-Phenylpropionic Acids by High-Performance Liquid Chromatography with Hydroxypropyl-β-Cyclodextrin as Chiral Mobile Phase Additive.  |  Tong, S., et al. 2016. J Chromatogr Sci. 54: 593-7. PMID: 26755500
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Phenylbutyric Acid, 5 g

sc-209247
5 g
$260.00