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2-Phenyl-4-quinolinecarboxylic acid (CAS 132-60-5)

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Alternate Names:
Cinchophen
Application:
2-Phenyl-4-quinolinecarboxylic acid is a powerful antimicrobial
CAS Number:
132-60-5
Purity:
99%
Molecular Weight:
249.26
Molecular Formula:
C16H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Phenyl-4-quinolinecarboxylic acid is a compound used in biochemistry research. It is a derivative of quinoline and contains a phenyl group and a carboxylic acid functional group. This compound has the ability to interact with enzymes and proteins, making it useful for studying biochemical pathways and protein function. 2-Phenyl-4-quinolinecarboxylic acid is used in the laboratory to investigate the structure and function of enzymes, as well as to study protein-ligand interactions. Its chemical structure allows it to bind to specific sites on proteins, making it useful for understanding the mechanisms of enzyme catalysis and protein regulation. In biochemistry, it is used for studying the molecular basis of various biological processes.


2-Phenyl-4-quinolinecarboxylic acid (CAS 132-60-5) References

  1. Surprising alteration of antibacterial activity of 5'-modified neomycin against resistant bacteria.  |  Zhang, J., et al. 2008. J Med Chem. 51: 7563-73. PMID: 19012394
  2. Poly[bis-(μ-hemihydrogen 2-phenyl-quinoline-4-carboxyl-ato-κN,O)silver(I)].  |  Zhang, X., et al. 2009. Acta Crystallogr Sect E Struct Rep Online. 65: m223. PMID: 21581814
  3. A highly sensitive and selective fluorescent sensor for detection of Al(3+) using a europium(III) quinolinecarboxylate.  |  Xu, W., et al. 2014. Inorg Chem. 53: 6497-9. PMID: 24956229
  4. Phosphorescent, Cyclometalated Cinchophen-Derived Platinum Complexes: Syntheses, Structures, and Electronic Properties.  |  Stacey, OJ., et al. 2015. Inorg Chem. 54: 6528-36. PMID: 26090894
  5. Design, synthesis and biological evaluation of 2-phenylquinoline-4-carboxamide derivatives as a new class of tubulin polymerization inhibitors.  |  Zhu, L., et al. 2017. Bioorg Med Chem. 25: 5939-5951. PMID: 28988750
  6. Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.  |  Oliveira, E., et al. 2018. ChemistryOpen. 7: 9-52. PMID: 29318095
  7. Thermal, spectral and magnetic studies of some first row transition metal complexes of 2-phenyl-4-quinolinecarboxylic acid  |  J.R. Allan, B. Carson, H.J. Bowley, D.L. Gerrard. 1989. Thermochimica Acta. 144: 187-194.
  8. Three New Coordination Compounds Based on 2-Phenyl-4-quinolinecarboxylic Acid and Nitrogenous Neutral Ligands: Syntheses, Structural Features, and Properties†  |  Xiang-Yang Hou, Xiao Wang, Feng Fu, Ji-Jiang Wang, Long Tang. 2013. Zeitschrift für anorganische und allgemeine Chemie. 639: 1254-1260.
  9. Crystal Structure, Multiplex Photoluminescence, and Magnetic Properties of a Series of Lanthanide Coordination Polymers Based on Quinoline Carboxylate Ligand  |  Wentao Xu†, Youfu Zhou*†, Decai Huang†, Wei Xiong†, Mingyi Su†‡, Kun Wang†‡, Shuo Han†, and Maochun Hong†. 2013. Crystal Growth & Design. 13: 5420–5432.
  10. X-ray structure of an amide-appended chloromercurated derivative of 2-phenylquinoline  |  C. -Y. Lin, W. Henderson & B. K. Nicholson. 2015. Journal of Structural Chemistry. 56: 948–952.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Phenyl-4-quinolinecarboxylic acid, 50 g

sc-225531
50 g
$80.00