Date published: 2025-12-2

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2-Phenethylamine (CAS 64-04-0)

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Alternate Names:
β-Phenylethylamine
CAS Number:
64-04-0
Purity:
≥98%
Molecular Weight:
121.18
Molecular Formula:
C8H11N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Phenethylamine, also known as Phenethylamine, is a compound that exerts its effects on various receptors and pathways in the brain. It interacts with the dopamine, serotonin, and norepinephrine systems, as well as the GABAergic and glutamatergic pathways. Moreover, 2-Phenethylamine has been demonstrated to stimulate adenylate cyclase, a critical enzyme involved in regulating various cellular processes. Its chemical structure resembles that of the neurotransmitter dopamine.


2-Phenethylamine (CAS 64-04-0) References

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  2. Simultaneous determination of 10 kinds of biogenic amines in rat plasma using high-performance liquid chromatography coupled with fluorescence detection.  |  Wang, X., et al. 2018. Biomed Chromatogr. 32: e4211. PMID: 29446845
  3. Separation of positional isomers of nine 2-phenethylamine-derived designer drugs by liquid chromatography-tandem mass spectrometry.  |  Grumann, C. and Auwärter, V. 2018. Drug Test Anal.. PMID: 29455470
  4. Study on the Binding Interaction of the α,α',δ,δ'-Tetramethylcucurbit[6]uril With Biogenic Amines in Solution and the Solid State.  |  Yang, L., et al. 2018. Front Chem. 6: 289. PMID: 30065925
  5. Assessment of the cytotoxic effects of aporphine prototypes on head and neck cancer cells.  |  Rodrigues-Junior, DM., et al. 2020. Invest New Drugs. 38: 70-78. PMID: 31102120
  6. Flexible high resolution-mass spectrometry approach for screening new psychoactive substances in urban wastewater.  |  Salgueiro-González, N., et al. 2019. Sci Total Environ. 689: 679-690. PMID: 31279214
  7. Photoactivatable Odorants for Chemosensory Research.  |  Gore, S., et al. 2020. ACS Chem Biol. 15: 2516-2528. PMID: 32865973
  8. 2-Phenylethylamine (PEA) Ameliorates Corticosterone-Induced Depression-Like Phenotype via the BDNF/TrkB/CREB Signaling Pathway.  |  Lee, YJ., et al. 2020. Int J Mol Sci. 21: PMID: 33265983
  9. The Effects of Different Processing Methods on the Levels of Biogenic Amines in Zijuan Tea.  |  Liu, D., et al. 2022. Foods. 11: PMID: 35563983
  10. Pharmacological Properties and Function of the PxOctβ3 Octopamine Receptor in Plutella xylostella (L.).  |  Zhu, H., et al. 2022. Insects. 13: PMID: 36005359
  11. Dietary supplement mislabelling: case study on selected slimming products by developing a green isocratic HPLC method for their quality control.  |  El Azab, NF., et al. 2022. Sci Rep. 12: 22305. PMID: 36566240
  12. The Development of an Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Biogenic Amines in Fish Samples.  |  Li, T., et al. 2022. Molecules. 28: PMID: 36615379
  13. The detection, identification and measurement of indole, tryptamine and 2-phenethylamine in putrefying human tissue.  |  Oliver, JS., et al. 1977. Forensic Sci. 9: 195-203. PMID: 863352

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Phenethylamine, 50 ml

sc-238192
50 ml
$46.00