2-Palmitoylglycerol CAS: 23470-00-0
MF: C19H38O4
MW: 330.51
A fatty acid glycerol ester that enhances 2-arachidonoylglycerol.

2-Palmitoylglycerol (CAS 23470-00-0)

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Synonym: Hexadecanoic Acid 2-Hydroxy-1-(hydroxymethyl)ethyl Ester
Application: A fatty acid glycerol ester that enhances 2-arachidonoylglycerol
CAS Number: 23470-00-0
Molecular Weight: 330.51
Molecular Formula: C19H38O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Palmitoylglycerol is a fatty acid ester, which increases the ability of 2-arachidonoylglycerol (sc-200794) to bind to CB1 and CB2 cannabinoid receptors. Studies indicate that 2-Palmitoylglycerol also increases the inhibitory activity of 2-arachidonylglycerol on adenylyl cyclase. The inhibitory effects of 2-arachidonylglycerol on TNF α (tumor necrosis factor-α) by mouse macrophages is enhanced in the presence of 2-Palmitoylglycerol. Furthermore, 2-Palmitoylglycerol may be a key component in modulating pain sensitivity as a result of its ability to interact with endocannabinoids.


References

1. Ben-Shabat, S., et al. 1998. Eur. J. Pharmacol. 353: 23-31. PMID: 9721036
2. Gallily, R., et al. 2000. Eur. J. Pharmacol. 406: R5-7. PMID: 11011050
3. Walker, J.M., et al. 2002. Chem. Phys. Lipids 121: 159-172. PMID: 12505698

Physical State :
Solid
Solubility :
Soluble in ethanol (100 mM), DMSO (100 mM), chloroform, and ethyl acetate.
Storage :
Store at -20° C
Melting Point :
151.08° C (Predicted)
Boiling Point :
~460.6° C at 760 mmHg (Predicted)
Density :
~1.0 g/cm3 (Predicted)
Refractive Index :
n20D 1.47 (Predicted)
pK Values :
pKa: 13.54 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
123409
MDL Number :
MFCD00058513
SMILES :
CCCCCCCCCCCCCCCC(=O)OC(CO)CO

Download SDS (MSDS)

Certificate of Analysis

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