2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (CAS 26112-88-9)
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2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid is a derivative of sialic acid, and is a synthetic compound that has been utilized in various research endeavors since its synthesis in the 1960s. Its applications span across biochemical and physiological studies. It has played a role in exploring the binding interactions between sialic acid-containing glycans and their corresponding receptors, shedding light on important molecular recognition events. Additionally, it has been instrumental in deciphering the impact of sialic acid on the immune system, unraveling its immunomodulatory effects. Furthermore, it has contributed to the investigation of the structure and functionality of enzymes involved in sialic acid metabolism, deepening our understanding of these enzymatic processes.
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (CAS 26112-88-9) References
- Mutants of Micromonospora viridifaciens sialidase have highly variable activities on natural and non-natural substrates. | Jers, C., et al. 2015. Protein Eng Des Sel. 28: 37-44. PMID: 25573534
- Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. | Hentrich, K., et al. 2016. Cell Host Microbe. 20: 307-317. PMID: 27593514
- New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability. | Maurice, P., et al. 2016. Sci Rep. 6: 38363. PMID: 27917893
- Deacetylation of sialic acid by esterases potentiates pneumococcal neuraminidase activity for mucin utilization, colonization and virulence. | Kahya, HF., et al. 2017. PLoS Pathog. 13: e1006263. PMID: 28257499
- Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut. | Lim, B., et al. 2017. Cell. 169: 547-558.e15. PMID: 28431252
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid, 1 mg | sc-213882 | 1 mg | $255.00 | |||
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid, 5 mg | sc-213882A | 5 mg | $877.00 |