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2-O-α-L-Fucopyranosyl-D-galactose (CAS 24656-24-4)

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Alternate Names:
Fuc-(α1,2)-Gal; 2-O-(α-L-Fucopyranosyl)-D-galactopyranose; Blood Group H Disaccharide
Application:
2-O-α-L-Fucopyranosyl-D-galactose is used to form a new type of β-propeller architecture
CAS Number:
24656-24-4
Molecular Weight:
326.30
Molecular Formula:
C12H22O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-O-α-L-Fucopyranosyl-D-galactose is a compound of interest in scientific research, particularly in the field of glycobiology. This chemical plays a crucial role as a glycan component in various biological processes, including cell-cell recognition, cell adhesion, and immune response modulation. One notable research application involves its involvement in the biosynthesis of glycoconjugates and glycoproteins, where it serves as a key intermediate in the construction of complex oligosaccharide structures. Researchers utilize this compound as a substrate in enzymatic assays to investigate the specificity and catalytic mechanisms of glycosyltransferases and glycosidases involved in glycan biosynthesis and modification pathways. Furthermore, 2-O-α-L-Fucopyranosyl-D-galactose has been utilized in the synthesis of glycan-based probes and glycomimetics for studying carbohydrate-protein interactions and elucidating the roles of glycans in various biological processes. Its ability to mimic natural glycan structures makes it valuable in designing and developing glycan-based vaccines, and diagnostics. Additionally, this compound serves as a useful tool in glycoengineering strategies aimed at modulating cellular functions and signaling pathways for research purposes. Overall, 2-O-α-L-Fucopyranosyl-D-galactose contributes significantly to advancing our understanding of glycobiology and has promising applications in biomedical research and biotechnology.


2-O-α-L-Fucopyranosyl-D-galactose (CAS 24656-24-4) References

  1. Crystal structure of fucose-specific lectin from Aleuria aurantia binding ligands at three of its five sugar recognition sites.  |  Fujihashi, M., et al. 2003. Biochemistry. 42: 11093-9. PMID: 14503859
  2. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens.  |  Feizi, T. Nature. 314: 53-7. PMID: 2579340
  3. Glycosidases of aspergillus niger. II. Purification and general properties of 1,2-alpha-L-fucosidase.  |  Bahl, OP. 1970. J Biol Chem. 245: 299-304. PMID: 5460888
  4. Crystal state and solution conformation of the B blood group trisaccharide alpha-L-Fucp-(1-->2)-[alpha-D-Galp]-(1-->3)]-beta-D-Galp-OCH3.  |  Otter, A., et al. 1999. Eur J Biochem. 259: 295-303. PMID: 9914506
  5. Synthesis of benzyl 6-O-benzoyl-3,4-O-isopropylidene-β-D-galactopyranoside and of 2-O-α-L-fucopyranosyl-D-galactose  |  A. Levy, H.M. Flowers, N. Sharon. 1967. Carbohydrate Research. 4: 305-311.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-O-α-L-Fucopyranosyl-D-galactose, 5 mg

sc-220755
5 mg
$390.00