Molecular structure of 2-Nitrophenylhydrazine, CAS Number: 3034-19-3
2-Nitrophenylhydrazine (CAS 3034-19-3)
CAS Number:
3034-19-3
Purity:
97%
Molecular Weight:
153.14
Molecular Formula:
C6H7N3O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Nitrophenylhydrazine is a chemical compound that functions as a reagent in various chemical reactions. It acts as a nucleophile, participating in nucleophilic substitution reactions with electrophiles. 2-Nitrophenylhydrazine is known to form stable complexes with metal ions, making it useful in analytical chemistry for the detection and quantification of metal ions in solution. 2-Nitrophenylhydrazine is utilized in the synthesis of organic compounds, particularly in the preparation of hydrazones and other derivatives. Its mechanism of action involves the formation of covalent bonds with specific functional groups, allowing for the modification and transformation of organic molecules. In research and development, 2-Nitrophenylhydrazine plays a role in the development of new chemical entities and the investigation of reaction mechanisms. Its ability to react with various functional groups makes it useful for chemical synthesis and analysis.
2-Nitrophenylhydrazine (CAS 3034-19-3) References
- On-line determination of carboxylic acids, aldehydes and ketones by high-performance liquid chromatography-diode array detection-atmospheric pressure chemical ionisation mass spectrometry after derivatization with 2-nitrophenylhydrazine. | Peters, R., et al. 2004. J Chromatogr A. 1031: 35-50. PMID: 15058566
- [Determination of magnesium stearate in pharmaceutical preparations using derivatization with 2-nitrophenylhydrazine and HPLC]. | Arai, T. and Hosoi, Y. 2005. Yakugaku Zasshi. 125: 299-305. PMID: 15738629
- Occurrence of the free and Peptide forms of pyroglutamic acid in plasma from the portal blood of rats that had ingested a wheat gluten hydrolysate containing pyroglutamyl peptides. | Higaki-Sato, N., et al. 2006. J Agric Food Chem. 54: 6984-8. PMID: 16968052
- Determination of biotin following derivatization with 2-nitrophenylhydrazine by high-performance liquid chromatography with on-line UV detection and electrospray-ionization mass spectrometry. | Yomota, C. and Ohnishi, Y. 2007. J Chromatogr A. 1142: 231-5. PMID: 17234197
- Development and validation of a liquid chromatographic method for the determination of hydroxymethylfurfural and alpha-ketoglutaric acid in human plasma. | Michail, K., et al. 2007. Anal Chim Acta. 581: 287-97. PMID: 17386455
- Identification of drying oils used in pictorial works of art by liquid chromatography of the 2-nitrophenylhydrazides derivatives of fatty acids. | Peris Vicente, J., et al. 2004. Talanta. 64: 326-33. PMID: 18969607
- Determination of methotrexate and indomethacin in urine using SPE-LC-DAD after derivatization. | Michail, K. and Moneeb, MS. 2011. J Pharm Biomed Anal. 55: 317-24. PMID: 21330088
- Mass spectrometry analysis of 2-nitrophenylhydrazine carboxy derivatized peptides. | Zhang, J., et al. 2011. J Am Soc Mass Spectrom. 22: 1958-67. PMID: 21952763
- Derivatives of phenyl tribromomethyl sulfone as novel compounds with potential pesticidal activity. | Borys, KM., et al. 2012. Beilstein J Org Chem. 8: 259-65. PMID: 22423293
- Development of a Method for Measuring Phytanic Acid as a Lifestyle-related Disease Biomarker in Rat Serum Using Ultra-fast Liquid Chromatography-Ultraviolet Spectrophotometry Combined with a Modified 2-Nitrophenylhydrazine Derivatization Method. | Miyamoto, A., et al. 2017. Anal Sci. 33: 365-368. PMID: 28302979
- Development and validation of a general derivatization HPLC method for the trace analysis of acyl chlorides in lipophilic drug substances. | Zheng, X., et al. 2017. J Pharm Biomed Anal. 140: 327-333. PMID: 28391005
- Determination of total, free and esterified short-chain fatty acid in human serum by liquid chromatography-mass spectrometry. | Chen, Z., et al. 2019. Ann Clin Biochem. 56: 190-197. PMID: 30185055
- Determination of Short-Chain Fatty Acids in Mouse Feces by High-Performance Liquid Chromatography Using 2-Nitrophenylhydrazine as a Labeling Reagent. | Inoue, H., et al. 2019. Biol Pharm Bull. 42: 845-849. PMID: 31061330
- 2-Nitrophenylhydrazine: a selective reagent for colorimetric determination of carboxylic acid anhydrides and chlorides. | Munson, JW. 1974. J Pharm Sci. 63: 252-7. PMID: 4813249
- Colorimetric determination of aliphatic acids. | Munson, JW. and Bilous, R. 1977. J Pharm Sci. 66: 1403-5. PMID: 925894
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Nitrophenylhydrazine, 5 g | sc-238178 | 5 g | $72.00 |