Date published: 2025-12-16

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2-Nitrophenol (CAS 88-75-5)

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Application:
2-Nitrophenol is a building block used as an acid-base indicator
CAS Number:
88-75-5
Purity:
≥98%
Molecular Weight:
139.11
Molecular Formula:
C6H5NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Nitrophenol functions as a precursor in the synthesis of dyes and pesticides. It acts as a reagent in various organic reactions, including the preparation of nitrophenyl ethers and esters. In the research and development setting, 2-Nitrophenol undergoes reduction to form 2-Aminophenol, which is a key intermediate in the production of dyes. 2-Nitrophenol′s mechanism of action involves participating in nucleophilic aromatic substitution reactions, leading to the formation of diverse organic compounds. 2-Nitrophenol can serve as a starting material for the synthesis of complex molecules with potential applications in various fields. Its role in the laboratory setting involves its reactivity and ability to undergo specific chemical transformations, contributing to the development of new compounds and materials.


2-Nitrophenol (CAS 88-75-5) References

  1. Simultaneous determination of 2-nitrophenol and 4-nitrophenol based on the multi-wall carbon nanotubes Nafion-modified electrode.  |  Huang, W., et al. 2003. Anal Bioanal Chem. 375: 703-7. PMID: 12638057
  2. Aqueous atmospheric chemistry: formation of 2,4-dinitrophenol upon nitration of 2-nitrophenol and 4-nitrophenol in solution.  |  Vione, D., et al. 2005. Environ Sci Technol. 39: 7921-31. PMID: 16295857
  3. Decomposition of 2-nitrophenol in aqueous solution by ozone and UV/ozone processes.  |  Ku, Y., et al. 2006. Water Environ Res. 78: 901-8. PMID: 17120450
  4. Rat cytochromes P450 oxidize 2-nitrophenol, a human metabolite of carcinogenic 2-nitroanisole.  |  Svobodova, M., et al. 2009. Neuro Endocrinol Lett. 30 Suppl 1: 46-51. PMID: 20027144
  5. 2-Nitrophenol reduction promoted by S. putrefaciens 200 and biogenic ferrous iron: the role of different size-fractions of dissolved organic matter.  |  Zhu, Z., et al. 2014. J Hazard Mater. 279: 436-43. PMID: 25093552
  6. Kinetic study of the gas-phase reactions of chlorine atoms with 2-chlorophenol, 2-nitrophenol, and four methyl-2-nitrophenol isomers.  |  Bejan, I., et al. 2015. J Phys Chem A. 119: 4735-45. PMID: 25893980
  7. Structures of the 2-nitrophenol alkali complexes in solution and the solid state.  |  Reichelt, H., et al. 2015. J Chem Phys. 143: 044307. PMID: 26233129
  8. Formation of 2-nitrophenol from salicylaldehyde as a suitable test for low peroxynitrite fluxes.  |  Mikhed, Y., et al. 2016. Redox Biol. 7: 39-47. PMID: 26629950
  9. Efficient 2-Nitrophenol Chemical Sensor Development Based on Ce2O3 Nanoparticles Decorated CNT Nanocomposites for Environmental Safety.  |  Hussain, MM., et al. 2016. PLoS One. 11: e0166265. PMID: 27973600
  10. Decomposition byproducts induced by gamma radiation and their toxicity: the case of 2-nitrophenol.  |  Alsager, OA., et al. 2018. Environ Technol. 39: 967-976. PMID: 28393679
  11. Microwave-activated carbons from tucumã (Astrocaryum aculeatum) seed for efficient removal of 2-nitrophenol from aqueous solutions.  |  Umpierres, CS., et al. 2018. Environ Technol. 39: 1173-1187. PMID: 28443387
  12. Novel biochar and hydrochar for the adsorption of 2-nitrophenol from aqueous solutions: An approach using the PVSDM model.  |  Pauletto, PS., et al. 2021. Chemosphere. 269: 128748. PMID: 33139043
  13. Electrochemical Detection of 2-Nitrophenol Using a Glassy Carbon Electrode Modified with BaO Nanorods.  |  Alam, MM., et al. 2021. Chem Asian J. 16: 1475-1485. PMID: 33847437
  14. Electrochemical detection of 2-nitrophenol using a heterostructure ZnO/RuO2 nanoparticle modified glassy carbon electrode.  |  Uddin, MT., et al. 2019. RSC Adv. 10: 122-132. PMID: 35492545
  15. Accumulation and transport of phenol, 2-nitrophenol, and 4-nitrophenol in plant cuticles.  |  Shafer, WE. and Schönherr, J. 1985. Ecotoxicol Environ Saf. 10: 239-52. PMID: 4085383

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Nitrophenol, 5 g

sc-254287
5 g
$26.00

2-Nitrophenol, 100 g

sc-254287A
100 g
$39.00