Molecular structure of 2-Naphthyl isocyanate, CAS Number: 2243-54-1
2-Naphthyl isocyanate (CAS 2243-54-1)
CAS Number:
2243-54-1
Molecular Weight:
169.18
Molecular Formula:
C10H7NCO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
2-Naphthyl isocyanate′s ability to react with amino groups in proteins, peptides, and other biomolecules, making it useful for studying protein structure and function. 2-Naphthyl isocyanate form stable adducts with amino acids, label and track specific proteins within cells. 2-Naphthyl isocyanate is useful in the study of enzyme kinetics, as it can be used to modify the active sites of enzymes and investigate their mechanisms of action. 2-Naphthyl isocyanate has been in the development of new methods for protein purification and analysis.
2-Naphthyl isocyanate (CAS 2243-54-1) References
- Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1. | Goosen, TC., et al. 2001. J Pharmacol Exp Ther. 296: 198-206. PMID: 11123381
- Selective reactivities of isocyanates towards DNA bases and genotoxicity of methylcarbamoylation of DNA. | Tamura, N., et al. 1992. Mutat Res. 283: 97-106. PMID: 1381495
- Oxidative conversion by rat liver microsomes of 2-naphthyl isothiocyanate to 2-naphthyl isocyanate, a genotoxicant. | Lee, MS. 1992. Chem Res Toxicol. 5: 791-6. PMID: 1489930
- Biomarkers for isocyanate exposure: Synthesis of isocyanate DNA adducts. | Beyerbach, A., et al. 2006. Chem Res Toxicol. 19: 1611-8. PMID: 17173374
- Assessment of synthetic methods for the preparation of N-beta-d-glucopyranosyl-N'-substituted ureas, -thioureas and related compounds. | Somsák, L., et al. 2008. Carbohydr Res. 343: 2083-93. PMID: 18299124
- The chemistry of the organic isocyanates. | SAUNDERS, JH. and SLOCOMBE, RJ. 1948. Chem Rev. 43: 203-18. PMID: 18887957
- Photochemistry of 2-naphthoyl azide. An ultrafast time-resolved UV-vis and IR spectroscopic and computational study. | Kubicki, J., et al. 2011. J Am Chem Soc. 133: 9751-61. PMID: 21548657
- Characterization and genotoxicity of DNA adducts caused by 2-naphthyl isocyanate. | Tamura, N., et al. 1990. Carcinogenesis. 11: 2009-14. PMID: 2225333
- Ultrahigh-water-content supramolecular hydrogels exhibiting multistimuli responsiveness. | Appel, EA., et al. 2012. J Am Chem Soc. 134: 11767-73. PMID: 22758793
- Rhodium(III)-catalyzed amidation of aryl ketone O-methyl oximes with isocyanates by C-H activation: convergent synthesis of 3-methyleneisoindolin-1-ones. | Zhou, B., et al. 2013. Chemistry. 19: 4701-6. PMID: 23460480
- Interfacial assembly of dendritic microcapsules with host-guest chemistry. | Zheng, Y., et al. 2014. Nat Commun. 5: 5772. PMID: 25511608
- Preparation, characterization and antimicrobial activities of cyclic substituted chitosan derivatives. | Zhang, Z., et al. 2021. Int J Biol Macromol. 193: 474-480. PMID: 34699895
- Mutagenicity of the O-esters of N-acylhydroxylamines for Salmonella. | Wang, CY., et al. 1981. Chem Biol Interact. 34: 267-78. PMID: 7006836
- Oxidative conversion of isothiocyanates to isocyanates by rat liver. | Lee, MS. 1994. Environ Health Perspect. 102 Suppl 6: 115-8. PMID: 7889832
- Enzyme induction and comparative oxidative desulfuration of isothiocyanates to isocyanates. | Lee, MS. 1996. Chem Res Toxicol. 9: 1072-8. PMID: 8902261
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Naphthyl isocyanate, 1 g | sc-225504 | 1 g | $173.00 |