Molecular structure of 2-N-Methylaminoethyl chloride hydrohloride, CAS Number: 4535-90-4
2-N-Methylaminoethyl chloride hydrohloride (CAS 4535-90-4)
Alternate Names:
2-chloro-n-methyl-ethanamine hydrochloride
CAS Number:
4535-90-4
Purity:
≥97%
Molecular Weight:
130.02
Molecular Formula:
C3H8ClN•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-N-Methylaminoethyl chloride hydrohloride is a nitro compound specifically designed to act as an inhibitor of PD-1. PD-1 is a protein that plays a role in regulating immune responses. By targeting PD-1, this compound effectively hampers its function, resulting in enhanced T cell activity, heightened proliferation, and increased cytokine production. Notably, 2-N-Methylaminoethyl chloride hydrohloride has demonstrated substantial potency as a PD-1 inhibitor, with a Ki value of 2 nM. Furthermore, it exhibits inhibitory effects on PD-L1 at concentrations up to 10 μM.
2-N-Methylaminoethyl chloride hydrohloride (CAS 4535-90-4) References
- Site-Specific Installation of Succinyl Lysine Analog into Histones Reveals the Effect of H2BK34 Succinylation on Nucleosome Dynamics. | Jing, Y., et al. 2018. Cell Chem Biol. 25: 166-174.e7. PMID: 29249693
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-N-Methylaminoethyl chloride hydrohloride, 1 g | sc-288256 | 1 g | $120.00 | |||
2-N-Methylaminoethyl chloride hydrohloride, 5 g | sc-288256A | 5 g | $443.00 |