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2-Methylthio-2-imidazoline hydriodide (CAS 5464-11-9)

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Alternate Names:
2-Methylsulfanyl-4,5-dihydro-1H-imidazole hydrogen iodide
Application:
2-Methylthio-2-imidazoline hydriodide is a reactant for synthesis of: aurora and epidermal growth factor receptor kinase inhibitors
CAS Number:
5464-11-9
Purity:
≥99%
Molecular Weight:
244.10
Molecular Formula:
C4H8N2S•HI
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Methylthio-2-imidazoline hydriodide is a reactant for synthesis of: aurora and epidermal growth factor receptor kinase inhibitors, spiro-piperidine inhibitors, galegine analogues,guanidinyl pyrrolidines as bifunctional catalysts, carbonic anhydrase inhibitors and small molecule CXCR4 antagonists. Moreover, it has demonstrated anti-inflammatory and anti-tumor properties in medical research. Notably, 2-Methylthio-2-imidazoline hydriodide has also played a significant role in synthesizing various metal complexes, which hold potential applications in catalysis and drug delivery systems.


2-Methylthio-2-imidazoline hydriodide (CAS 5464-11-9) References

  1. N, N' (4,5-dihydro-1h-imidazol-2-yl)3-aza-1,10-decane-diamine and N, N'(4,5-dihydro-1H-imidazol-2-yl)3-aza-1, 10-dodecane-diamine antagonize cell proliferation as selective ligands towards topoisomerase II.  |  Filosa, R., et al. 2006. J Pharm Pharmacol. 58: 1415-20. PMID: 17034667
  2. Benzylguanidines and other galegine analogues inducing weight loss in mice.  |  Coxon, GD., et al. 2009. J Med Chem. 52: 3457-63. PMID: 19422230
  3. Design and synthesis of highly TRAIL expression HDAC inhibitors based on ONC201 to promote apoptosis of colorectal cancer.  |  Cui, H., et al. 2022. Eur J Med Chem. 238: 114484. PMID: 35649291
  4. Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones.  |  Temple, DL., et al. 1980. J Med Chem. 23: 1188-98. PMID: 6161252
  5. Syntheses and spectral properties of 2‐Thiobiotin and biotin derivatives  |  Flaster, H., & Kohn, H. 1981. Journal of Heterocyclic Chemistry. 18(7): 1425-1436.
  6. Heteroaromatic analogs of the. alpha. 2-adrenoreceptor partial agonist clonidine  |  Chapleo, C. B., Butler, R. C., England, D. C., Myers, P. L., Roach, A. G., Smith, C. F.,.. & Tulloch, I. F. 1989. Journal of medicinal chemistry. 32(7): 1627-1630.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methylthio-2-imidazoline hydriodide, 25 g

sc-230567
25 g
$92.00