Date published: 2025-12-3

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2-Methyltetrahydrothiophen-3-one (CAS 13679-85-1)

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Alternate Names:
2-Methyl-3-oxotetrahydrothiophene
Application:
2-Methyltetrahydrothiophen-3-one is a dually substituted thiophene with butter and balsamic organoleptic qualities
CAS Number:
13679-85-1
Molecular Weight:
116.18
Molecular Formula:
C5H8OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methyltetrahydrothiophen-3-one is an organic sulfur-containing compound that belongs to the class of tetrahydrothiophenes. This compound features a five-membered ring comprising four carbon atoms and one sulfur atom, with a ketone group at the 3-position and a methyl group attached to the 2-position of the ring. This structure makes it a valuable compound in various chemical research areas, particularly in the synthesis of heterocyclic compounds and the study of sulfur chemistry. The mechanism of action of 2-Methyltetrahydrothiophen-3-one primarily involves its role as a reactive intermediate and a building block in organic synthesis. The ketone functionality allows it to undergo a range of typical carbonyl group reactions, including nucleophilic addition and condensation reactions. These properties are utilized to synthesize larger, more complex molecules, especially those containing sulfur heterocycles, which are of interest in developing new materials and chemicals with specific functional properties. In scientific research, 2-Methyltetrahydrothiophen-3-one is used to study the chemistry of thiophenes and their derivatives. Researchers explore how the introduction of sulfur and additional substituents affects the electronic and steric properties of the molecule. This research helps in understanding the behavior of sulfur-containing heterocyclic compounds in various chemical environments and their potential reactivity patterns. Additionally, this compound is involved in the synthesis of pharmaceuticals and agrochemicals, where sulfur-containing heterocycles play a crucial role in biological activity. By studying the reactivity of 2-Methyltetrahydrothiophen-3-one, chemists can design and synthesize novel compounds with potential bioactivity, exploring how the thiophene structure influences binding and interaction with biological targets.


2-Methyltetrahydrothiophen-3-one (CAS 13679-85-1) References

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  5. Meat flavor generation from different composition patterns of initial Maillard stage intermediates formed in heated cysteine-xylose-glycine reaction systems.  |  Zhao, J., et al. 2019. Food Chem. 274: 79-88. PMID: 30373010
  6. Identification of the key off-flavor odorants for undesirable spoiled odor in thermally sterilized fermented soymilk.  |  Hao, Z., et al. 2023. Food Res Int. 164: 112407. PMID: 36737988
  7. Multidimensional Gas Chromatography of Organosulfur Compounds in Coffee and Structure-Odor Analysis of 2-Methyltetrahydrothiophen-3-one.  |  Pua, A., et al. 2023. J Agric Food Chem. 71: 4337-4345. PMID: 36861492

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methyltetrahydrothiophen-3-one, 5 g

sc-265828
5 g
$120.00

2-Methyltetrahydrothiophen-3-one, 25 g

sc-265828A
25 g
$548.00