Date published: 2025-12-18

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2-Methylbutane (CAS 78-78-4)

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Alternate Names:
isopentane
Application:
2-Methylbutane is a hydrocarbon used in flash freezing
CAS Number:
78-78-4
Purity:
≥97%
Molecular Weight:
72.15
Molecular Formula:
C5H12
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methylbutane is one of the most widely used hydrocarbons in the world, suitable for flash freezing of biological samples. When heated, the hydrogen atoms bond to the carbon atoms to form a hydrocarbon chain. This chain can then be broken down into smaller molecules, such as propane, butane, ethane, and methane. 2-Methylbutane has been used in a variety of scientific research applications, including the study of the effects of hydrocarbons on the environment, and the development of new materials for use in industry. It has been employed in the production of gasoline, polymers, solvents, lubricants, and polyurethane foam.


2-Methylbutane (CAS 78-78-4) References

  1. Electrophilic oxidant produced in the photodeoxygenation of 1,2-benzodiphenylene sulfoxide.  |  Lucien, E. and Greer, A. 2001. J Org Chem. 66: 4576-9. PMID: 11421776
  2. Intermediates in the autoxidation of nitrogen monoxide.  |  Galliker, B., et al. 2009. Chemistry. 15: 6161-8. PMID: 19437472
  3. Proton phototransfers in doubly hydrogen bonded dimers: the photophysics of 6,7,8,9-tetrahydro-5H-pyrido[2,3-b]indole dimers.  |  Catalán, J. 2010. J Phys Chem A. 114: 811-6. PMID: 20017468
  4. One-generation reproductive toxicity study of 2-methylbutane in Sprague-Dawley rats.  |  Yu, WJ., et al. 2011. Regul Toxicol Pharmacol. 60: 136-43. PMID: 21419187
  5. A Study of Micronucleus Induction with Methyl Formate and 2-Methylbutane in Bone Marrow Cells of Male ICR Mice.  |  Kim, SJ., et al. 2010. Saf Health Work. 1: 80-6. PMID: 22953166
  6. A spectroscopic rule from the solvatochromism of aromatic solutes in nonpolar solvents.  |  Catalán, J. and Del Valle, JC. 2014. J Phys Chem B. 118: 5168-76. PMID: 24735522
  7. Tissue triage and freezing for models of skeletal muscle disease.  |  Meng, H., et al. 2014. J Vis Exp.. PMID: 25078247
  8. Long-Term Incubation Reveals Methanogenic Biodegradation of C5 and C6 iso-Alkanes in Oil Sands Tailings.  |  Siddique, T., et al. 2015. Environ Sci Technol. 49: 14732-9. PMID: 26571341
  9. Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation.  |  Hoyt, LR., et al. 2016. J Immunol. 197: 1322-34. PMID: 27421477
  10. Screening metal-organic frameworks for separation of pentane isomers.  |  Krishna, R. and van Baten, JM. 2017. Phys Chem Chem Phys. 19: 8380-8387. PMID: 28282097
  11. Low-Temperature Trapping of Intermediates in the Reaction of NO• with O2.  |  Mahmoudi, L., et al. 2017. Inorg Chem. 56: 4846-4851. PMID: 28414428
  12. Comprehensive Autopsy Program for Individuals with Multiple Sclerosis.  |  Dutta, R., et al. 2019. J Vis Exp.. PMID: 31380830
  13. Methanogenic Biodegradation of iso-Alkanes by Indigenous Microbes from Two Different Oil Sands Tailings Ponds.  |  Mohamad Shahimin, MF., et al. 2021. Microorganisms. 9: PMID: 34442648
  14. Tissue cryopreservation using the 3M™ Novec™ 7000 freezing coolant offers a comparable and safe alternative to customary coolants.  |  Nunez, V., et al. 2022. J Histotechnol. 45: 85-91. PMID: 34787535
  15. The use of propane/isopentane mixtures for rapid freezing of biological specimens.  |  Jehl, B., et al. 1981. J Microsc. 123: 307-9. PMID: 7299814

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methylbutane, 25 ml

sc-238147
25 ml
$45.00

2-Methylbutane, 500 ml

sc-238147A
500 ml
$73.00