Molecular structure of 2-methyladenosine, CAS Number: 16526-56-0
2-methyladenosine (CAS 16526-56-0)
CAS Number:
16526-56-0
Purity:
≥95%
Molecular Weight:
281.27
Molecular Formula:
C11H15N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-methyladenosine is a glutamate receptor inhibitor that exhibits anti-seizure activity. 2-Methyladenosine, a naturally occurring nucleoside belonging to the purine family, plays a role in various biological processes. It is an integral part of RNA, contributing to the adenine-uracil base pairing. Its significance extends to processes like transcriptional regulation, RNA splicing, and translation. It interacts with adenosine receptors present on cell surfaces, influencing cellular processes. Furthermore, it engages with enzymes involved in gene expression regulation, such as RNA polymerase II and histone deacetylases.
2-methyladenosine (CAS 16526-56-0) References
- 2-Methyladenosine-Substituted 2',5'-oligoadenylates: conformations, 2-5A binding and catalytic activities with human ribonuclease L. | Kitade, Y., et al. 2000. Bioorg Med Chem Lett. 10: 329-31. PMID: 10714492
- Primary structure of tRNA Arg II of E. coli B. | Chakraburtty, K. 1975. Nucleic Acids Res. 2: 1787-92. PMID: 1103085
- The metabolism of 2-methyladenosine in Mycobacterium smegmatis. | Chen, CK., et al. 2002. Microbiology (Reading). 148: 289-295. PMID: 11782521
- Identification and characterization of a unique adenosine kinase from Mycobacterium tuberculosis. | Long, MC., et al. 2003. J Bacteriol. 185: 6548-55. PMID: 14594827
- Metabolism of 2-methyladenosine in Mycobacterium tuberculosis. | Parker, WB., et al. 2004. Tuberculosis (Edinb). 84: 327-36. PMID: 15207808
- Overexpression, purification and crystallographic analysis of a unique adenosine kinase from Mycobacterium tuberculosis. | Wang, Y., et al. 2005. Acta Crystallogr Sect F Struct Biol Cryst Commun. 61: 553-7. PMID: 16511094
- Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry. | Li, HY., et al. 2009. J Mass Spectrom. 44: 641-51. PMID: 19142897
- miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes. | Stojković, V., et al. 2018. J Am Chem Soc. 140: 7135-7143. PMID: 29782154
- A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. | Vangaveti, S., et al. 2020. J Mol Biol. 432: 913-929. PMID: 31945376
- Structure and stability of complexes between poly-5-bromouridylic acid and 2,9-dimethyladenine or 2-methyladenosine. | Higuchi, S. and Yasui, K. 1980. Nucleic Acids Symp Ser. s143-5. PMID: 7255186
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-methyladenosine, 5 mg | sc-500888 | 5 mg | $393.00 |