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2-Methyl-thiazolidine-4-carboxylic acid (CAS 4165-32-6)

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CAS Number:
4165-32-6
Molecular Weight:
147.2
Molecular Formula:
C5H9NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methyl-thiazolidine-4-carboxylic acid is a compound frequently utilized in the synthesis of biologically active molecules and in the study of amino acid metabolism. Its incorporation into larger molecules is of particular interest in the design of enzyme inhibitors, where it can mimic natural substrates or intermediates. Additionally, it is used in the study of peptide mimetics, providing insights into protein-protein interactions and enzyme catalysis. In biochemical research, 2-Methyl-thiazolidine-4-carboxylic acid is explored for its role in modulating metabolic pathways, particularly those related to amino acid biosynthesis and degradation. The compound is also used as a starting material for the preparation of various cyclic and acyclic compounds, which are analyzed for their potential industrial applications.


2-Methyl-thiazolidine-4-carboxylic acid (CAS 4165-32-6) References

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  2. Formaldehyde scavenging from peritoneal dialysis solutions using reduced aminothiol compounds.  |  Bird, SD., et al. 2004. Nephrology (Carlton). 9: 65-72. PMID: 15056264
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  4. Permeability and toxicity characteristics of L-cysteine and 2-methyl-thiazolidine-4-carboxylic acid in Caco-2 cells.  |  Kartal-Hodzic, A., et al. 2013. Pharm Dev Technol. 18: 1288-93. PMID: 22356486
  5. Determination of 2-carboxy thiazolidine-4-carboxylic acid in biological fluids by ion-exchange chromatography.  |  Alary, J., et al. 1989. J Pharm Biomed Anal. 7: 715-23. PMID: 2490775
  6. Mass spectrometric analysis of L-cysteine metabolism: physiological role and fate of L-cysteine in the enteric protozoan parasite Entamoeba histolytica.  |  Jeelani, G., et al. 2014. mBio. 5: e01995. PMID: 25370494
  7. Entamoeba thiol-based redox metabolism: A potential target for drug development.  |  Jeelani, G. and Nozaki, T. 2016. Mol Biochem Parasitol. 206: 39-45. PMID: 26775086
  8. Conjugation of acetaldehyde with cysteinylglycine, the first metabolite in glutathione breakdown by gamma-glutamyltranspeptidase.  |  Kera, Y., et al. 1985. Agents Actions. 17: 48-52. PMID: 2867670
  9. A novel quantification method for sulfur-containing biomarkers of formaldehyde and acetaldehyde exposure in human urine and plasma samples.  |  Landmesser, A., et al. 2020. Anal Bioanal Chem. 412: 7535-7546. PMID: 32840653
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  12. Ethanol-induced changes in the content of thiol compounds and of lipid peroxidation in livers and brains from mice: protection by thiazolidine derivatives.  |  Wlodek, L. and Rommelspacher, H. 1994. Alcohol Alcohol. 29: 649-57. PMID: 7695779
  13. Transamination and transsulphuration of L-cysteine in Ehrlich ascites tumor cells and mouse liver. The nonenzymatic reaction of L-cysteine with pyruvate.  |  Włodek, L., et al. 1993. Int J Biochem. 25: 107-12. PMID: 8094343
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methyl-thiazolidine-4-carboxylic acid, 500 mg

sc-308430
500 mg
$370.00