Date published: 2026-5-2

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2-Methyl-8-quinolinol (CAS 826-81-3)

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Alternate Names:
8-Hydroxyquinaldine
CAS Number:
826-81-3
Molecular Weight:
159.18
Molecular Formula:
C10H9NO
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methyl-8-quinolinol is a compound that functions as a chelating agent in various experimental. Its mode of action involves forming stable complexes with metal ions, particularly transition metals such as copper and iron. This chelation process allows 2-Methyl-8-quinolinol to effectively sequester metal ions, preventing their participation in redox reactions or other metal-dependent processes. In development settings, is utilized for its ability to modulate metal ion concentrations and influence metal-catalyzed reactions. By sequestering metal ions, 2-Methyl-8-quinolinol can impact the behavior of metalloenzymes and other metal-dependent biomolecules, provided with to investigate the role of metal ions in various biological processes. The chelating properties of 2-Methyl-8-quinolinol make it a compound for studying metal ion homeostasis and the impact of metal ion dysregulation on cellular function.


2-Methyl-8-quinolinol (CAS 826-81-3) References

  1. Synergistic effect of 3,5-dichlorophenol and trioctylphosphine oxide on the extraction of vanadium(V) with 2-methyl-8-quinolinol derivatives.  |  Tsuguchi, A., et al. 2002. Anal Sci. 18: 1227-33. PMID: 12458708
  2. Performance of tris(2-methyl-8-quinolinolato)aluminum as fluorescent anionophore.  |  Yuchi, A., et al. 2003. Anal Sci. 19: 1177-81. PMID: 12945673
  3. Synergistic cloud point extraction behavior of aluminum(III) with 2-methyl-8-quinolinol and 3,5-dichlorophenol.  |  Ohashi, A., et al. 2004. Anal Sci. 20: 1091-3. PMID: 15293409
  4. Reaction of 8-Quinolinol and 2-Methyl-8-Quinolinol with Rare-Earth Elements.  |  Wendlandt, WW. 1957. Science. 125: 1042-3. PMID: 17791109
  5. Supercritical carbon dioxide extraction equilibrium of gallium(III) with 2-methyl-8-quinolinol and 2-methyl-5-butyloxymethyl-8-quinolinol.  |  Choi, SY., et al. 2002. Talanta. 56: 689-97. PMID: 18968544
  6. Extraction equilibrium of palladium(II) with 2-methyl-8-quinolinol into supercritical carbon dioxide fluid.  |  Ougiyanagi, J., et al. 2002. Talanta. 57: 213-21. PMID: 18968621
  7. Solvent effect on distribution ratio of Pd(II) in supercritical carbon dioxide extraction and solvent extraction using 2-methyl-8-quinolinol.  |  Ougiyanagi, J., et al. 2003. Talanta. 59: 1189-98. PMID: 18969009
  8. Cloud point extraction of iron(III) and vanadium(V) using 8-quinolinol derivatives and Triton X-100 and determination of 10(-7)moldm(-3) level iron(III) in riverine water reference by a graphite furnace atomic absorption spectroscopy.  |  Ohashi, A., et al. 2005. Talanta. 65: 525-30. PMID: 18969830
  9. [Synthesis and antimicrobial ivestigation of 8-quinolinols glucosaminides].  |  Chupakhina, TA., et al. 2012. Bioorg Khim. 38: 482-8. PMID: 23189563
  10. Structural dynamics of nitrosylruthenium isomeric complexes studied with steady-state and transient pump-probe infrared spectroscopies.  |  Zhao, Y., et al. 2016. Spectrochim Acta A Mol Biomol Spectrosc. 166: 62-67. PMID: 27209490
  11. Differentiating Two Nitrosylruthenium Isomeric Complexes by Steady-State and Ultrafast Infrared Spectroscopies.  |  Yu, P., et al. 2016. J Phys Chem B. 120: 11502-11509. PMID: 27755866
  12. Exploring the charge transfer dynamics of hydrogen bonded crystals of 2-methyl-8-quinolinol and chloranilic acid: synthesis, spectrophotometric, single-crystal, DFT/PCM analysis, antimicrobial, and DNA binding studies.  |  Manojkumar, P., et al. 2021. RSC Adv. 11: 39994-40010. PMID: 35494159
  13. Antifungal activity of 5-, 7-, and 5,7-substituted 2-methyl-8-quinolinols.  |  Gershon, H., et al. 1972. Antimicrob Agents Chemother. 1: 373-5. PMID: 4670476

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methyl-8-quinolinol, 100 g

sc-238141
100 g
$35.00