Molecular structure of 2-Methyl-6-nitrobenzoic anhydride, CAS Number: 434935-69-0
2-Methyl-6-nitrobenzoic anhydride (CAS 434935-69-0)
See product citations (1)
Alternate Names:
MNBA
CAS Number:
434935-69-0
Purity:
>98%
Molecular Weight:
344.28
Molecular Formula:
C16H12N2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
2-Methyl-6-nitrobenzoic anhydride (2M6NBA) is an organic compound characterized by the molecular formula C9H6NO4. This colorless solid exhibits insolubility in water and possesses a melting point within the range of 165-168°C. The scientific research applications of 2-Methyl-6-nitrobenzoic anhydride are extensive. It is utilized as a reagent in chiral compound synthesis, a catalyst in organic reactions, and an intermediate in the production of pharmaceuticals and agrochemicals. Moreover, it plays a pivotal role in synthesizing various organic compounds, including heterocycles, and peptide analogs. Acting as a catalyst, 2-Methyl-6-nitrobenzoic anhydride activates the reactants and enhances the reaction rate.
2-Methyl-6-nitrobenzoic anhydride (CAS 434935-69-0) References
- An effective use of benzoic anhydride and its derivatives for the synthesis of carboxylic esters and lactones: a powerful and convenient mixed anhydride method promoted by basic catalysts. | Shiina, I., et al. 2004. J Org Chem. 69: 1822-30. PMID: 15058924
- Enantioselective total synthesis of octalactin a using asymmetric aldol reactions and a rapid lactonization to form a medium-sized ring. | Shiina, I., et al. 2005. Chemistry. 11: 6601-8. PMID: 16118824
- Highly sensitive determination of estrone and estradiol in human serum by liquid chromatography-electrospray ionization tandem mass spectrometry. | Yamashita, K., et al. 2007. Steroids. 72: 819-27. PMID: 17716700
- Use of novel picolinoyl derivatization for simultaneous quantification of six corticosteroids by liquid chromatography-electrospray ionization tandem mass spectrometry. | Yamashita, K., et al. 2007. J Chromatogr A. 1173: 120-8. PMID: 17964584
- 4-(Dimethylamino)pyridine N-oxide (DMAPO): an effective nucleophilic catalyst in the peptide coupling reaction with 2-methyl-6-nitrobenzoic anhydride. | Shiina, I., et al. 2008. Chem Asian J. 3: 454-61. PMID: 18219641
- Simultaneous determination of tetrahydrocortisol, allotetrahydrocortisol and tetrahydrocortisone in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry. | Yamashita, K., et al. 2008. Steroids. 73: 727-37. PMID: 18394666
- Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids. | Yamashita, K., et al. 2008. J Chromatogr A. 1200: 114-21. PMID: 18561939
- Fusaric acid as a novel proton-affinitive derivatizing reagent for highly sensitive quantification of hydroxysteroids by LC-ESI-MS/MS. | Yamashita, K., et al. 2010. J Am Soc Mass Spectrom. 21: 249-53. PMID: 19914845
- Evaluation of the efficiency of the macrolactonization using MNBA in the synthesis of erythromycin A aglycon. | Shiina, I., et al. 2009. Chem Rec. 9: 305-20. PMID: 20041452
- Total synthesis of cyanolide A and confirmation of its absolute configuration. | Kim, H. and Hong, J. 2010. Org Lett. 12: 2880-3. PMID: 20491466
- Significant enhancement of 11-Hydroxy-THC detection by formation of picolinic acid esters and application of liquid chromatography/multi stage mass spectrometry (LC-MS(3)): Application to hair and oral fluid analysis. | Thieme, D., et al. 2015. Drug Test Anal. 7: 577-85. PMID: 25345394
- Antineoplastic agents. 599. Total synthesis of dolastatin 16. | Pettit, GR., et al. 2015. J Nat Prod. 78: 476-85. PMID: 25689568
- [Total Synthesis of Biologically Active Natural Products toward Elucidation of the Mode of Action]. | Yoshida, M. 2015. Yakugaku Zasshi. 135: 1099-108. PMID: 26423864
- Solid-Phase Combinatorial Synthesis and Biological Evaluation of Destruxin E Analogues. | Yoshida, M., et al. 2015. Chemistry. 21: 18417-30. PMID: 26531322
- 4-(Dimethylamino)pyridine N-Oxide-Catalyzed Macrolactamization Using 2-Methyl-6-nitrobenzoic Anhydride in the Synthesis of the Depsipeptidic Analogue of FE399. | Tonoi, T., et al. 2021. ACS Omega. 6: 3571-3577. PMID: 33585740
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Methyl-6-nitrobenzoic anhydride, 1 g | sc-251782 | 1 g | $56.00 |