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2-Methyl-4,6-dinitrophenol serves as a metabolic uncoupler in experimental applications. It disrupts the process of oxidative phosphorylation in mitochondria by dissipating the proton gradient across the inner mitochondrial membrane. At the molecular level, 2-Methyl-4,6-dinitrophenol acts by allowing protons to freely re-enter the mitochondrial matrix, uncoupling the process of ATP synthesis from the electron transport chain. 2-Methyl-4,6-Dinitrophenol′s mechanism of action involves interfering with the normal flow of electrons in the respiratory chain, leading to the dissipation of energy as heat instead of the production of ATP. In experimental applications, 2-Methyl-4,6-dinitrophenol is used to study the regulation of energy metabolism and the physiological consequences of uncoupling oxidative phosphorylation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Methyl-4,6-dinitrophenol, 250 mg | sc-238139 | 250 mg | $32.00 | |||
2-Methyl-4,6-dinitrophenol, 1 g | sc-238139A | 1 g | $64.00 | |||
2-Methyl-4,6-dinitrophenol, 5 g | sc-238139B | 5 g | $128.00 | |||
2-Methyl-4,6-dinitrophenol, 10 g | sc-238139C | 10 g | $194.00 |