Date published: 2025-12-19

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2-Methyl-2-nitro-1,3-propanediol (CAS 77-49-6)

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CAS Number:
77-49-6
Molecular Weight:
135.12
Molecular Formula:
C4H9NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methyl-2-nitro-1,3-propanediol is a nitroalkane compound that has found use in biochemical studies. It serves as a tool for investigating the mechanisms of enzyme-catalyzed reactions and determining enzyme activity. It has been employed in the synthesis of novel compounds, including nitroalkanes and nitroaromatics. Additionally, 2-Methyl-2-nitro-1,3-propanediol exhibits utility in compound detection, enabling the identification of various substances such as nitroaromatics and chlorinated hydrocarbons.


2-Methyl-2-nitro-1,3-propanediol (CAS 77-49-6) References

  1. Aliphatic beta-nitroalcohols for therapeutic corneoscleral cross-linking: chemical mechanisms and higher order nitroalcohols.  |  Paik, DC., et al. 2010. Invest Ophthalmol Vis Sci. 51: 836-43. PMID: 19797229
  2. Using the Griess colorimetric nitrite assay for measuring aliphatic β-nitroalcohols.  |  Wen, Q. and Paik, DC. 2012. Exp Eye Res. 98: 52-7. PMID: 22406005
  3. Aliphatic β-nitroalcohols for therapeutic corneoscleral cross-linking: corneal permeability considerations.  |  Wen, Q., et al. 2013. Cornea. 32: 179-84. PMID: 22868628
  4. Aliphatic β-nitroalcohols for therapeutic corneoscleral cross-linking: chemical stability studies using 1H-NMR spectroscopy.  |  Li, X., et al. 2014. Photochem Photobiol. 90: 338-43. PMID: 23998198
  5. Mechanistic and Catalytic Studies of β-Nitroalcohol Crosslinking with Polyamine.  |  Li, X., et al. 2013. J Appl Polym Sci. 128: 3696-3701. PMID: 24596431
  6. Reactivities of substituted α-phenyl-N-tert-butyl nitrones.  |  Rosselin, M., et al. 2014. J Org Chem. 79: 6615-26. PMID: 24968285

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methyl-2-nitro-1,3-propanediol, 5 g

sc-275010
5 g
$74.00