Date published: 2025-12-16

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2-Methoxyfuran (CAS 25414-22-6)

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CAS Number:
25414-22-6
Molecular Weight:
98.10
Molecular Formula:
C5H6O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Methoxyfuran is used in organic chemistry research, particularly in the synthesis of heterocyclic compounds. Its presence in synthetic routes helps in the formation of various furan derivatives which are explored for their potential applications in different industrial fields such as materials science. Additionally, 2-Methoxyfuran is utilized in studies focusing on reaction mechanisms involving furans, providing insights into their reactivity and stability under various conditions. It also plays a role in the development of organic synthesis methodologies, contributing to the creation of more efficient and sustainable chemical processes. Furthermore, 2-Methoxyfuran is examined for its physical and chemical properties, aiding in the advancement of knowledge regarding the behavior of oxygen-containing heterocycles in complex chemical systems.


2-Methoxyfuran (CAS 25414-22-6) References

  1. Adventures with heterocycles.  |  Huisgen, R. 2000. Chem Pharm Bull (Tokyo). 48: 757-65. PMID: 10866132
  2. One-pot stereoselective synthesis of tricyclic bislactones from 2-pyrones and 2-methoxyfuran.  |  Chen, CH. and Liao, CC. 2000. Org Lett. 2: 2049-52. PMID: 10891227
  3. Vinylogous Mannich reactions: some theoretical studies on the origins of diastereoselectivity.  |  Bur, SK. and Martin, SF. 2000. Org Lett. 2: 3445-7. PMID: 11082005
  4. Cyclopropanation of enantiopure metal alkenyl carbenes with 2-methoxyfuran: a practical route to carboxycyclopropylglycine precursors.  |  Barluenga, J., et al. 2007. Chemistry. 13: 1326-31. PMID: 17075948
  5. A 4-alkyl-substituted analogue of guaiacol shows greater repellency to savannah tsetse (Glossina spp.).  |  Saini, RK. and Hassanali, A. 2007. J Chem Ecol. 33: 985-95. PMID: 17404820
  6. Asymmetric Friedel-Crafts alkylation of methoxyfuran with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline)-Zn(II) complexes.  |  Liu, H., et al. 2007. Org Lett. 9: 4725-8. PMID: 17924637
  7. Structural studies on cycloadducts of furan, 2-methoxyfuran, and 5-trimethylsilylcyclopentadiene with maleic anhydride and N-methylmaleimide.  |  Goh, YW., et al. 2008. J Org Chem. 73: 151-6. PMID: 18069850
  8. Structure and thermochemical properties of 2-methoxyfuran, 3-methoxyfuran, and their carbon-centered radicals using computational chemistry.  |  Hudzik, JM. and Bozzelli, JW. 2010. J Phys Chem A. 114: 7984-95. PMID: 20666545
  9. Pyrolysis Pathways of the Furanic Ether 2-Methoxyfuran.  |  Urness, KN., et al. 2015. J Phys Chem A. 119: 9962-77. PMID: 26351733
  10. Synthesis of Bis(oxazoline) Ligands Possessing C-5 gem-Disubstitution and Their Application in Asymmetric Friedel-Crafts Alkylations.  |  O'Reilly, S., et al. 2015. J Org Chem. 80: 10177-86. PMID: 26406290
  11. Chiral Brønsted acid-catalyzed enantioselective Friedel-Crafts reaction of 2-methoxyfuran with aliphatic ketimines generated in situ.  |  Kondoh, A., et al. 2016. Chem Sci. 7: 1057-1062. PMID: 29862000
  12. Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma.  |  Gui, X., et al. 2023. Clin Chim Acta. 541: 117235. PMID: 36716909

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methoxyfuran, 5 g

sc-225454
5 g
$204.00