Date published: 2026-4-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

2-Methoxy Estrone (CAS 362-08-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2-Hydroxyestrone 2-methyl ether
CAS Number:
362-08-3
Molecular Weight:
300.39
Molecular Formula:
C19H24O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Methoxy Estrone is a naturally occurring metabolite of the hormone estrogen. It is derived from estrone, which is one of the three major forms of estrogen produced in the human body. 2-Methoxyestrone is characterized by the addition of a methoxy group (-OCH3) at the 2-position of the estrone molecule.


2-Methoxy Estrone (CAS 362-08-3) References

  1. The conversion of 2-hydroxyestradiol-17 beta to 2-hydroxy and 2-methoxy metabolites in human urine.  |  AXELROD, LR., et al. 1961. Arch Biochem Biophys. 94: 265-8. PMID: 13685342
  2. 2-methoxyestrone as an estrogen metabolite in the human subject.  |  HOBKIRK, R. and NILSEN, M. 1963. J Clin Endocrinol Metab. 23: 274-8. PMID: 13954881
  3. Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture.  |  Weber, S., et al. 2005. Appl Microbiol Biotechnol. 67: 106-12. PMID: 15290133
  4. Estrogen metabolites in the release of inflammatory mediators from human amnion-derived cells.  |  Pavan, B., et al. 2011. Life Sci. 88: 551-8. PMID: 21277863
  5. Total dietary fat and omega-3 fatty acids have modest effects on urinary sex hormones in postmenopausal women.  |  Young, LR., et al. 2013. Nutr Metab (Lond). 10: 36. PMID: 23618064
  6. Qualitative and quantitative differences in estrogen biotransformation in human breast glandular and adipose tissues: implications for studies using mammary biospecimens.  |  Pemp, D., et al. 2019. Arch Toxicol. 93: 2823-2833. PMID: 31489452
  7. The metabolism of estradiol; oral compared to intravenous administration.  |  Longcope, C., et al. 1985. J Steroid Biochem. 23: 1065-70. PMID: 4094413
  8. Comparative fate of estrone and estrone sulfate in man.  |  Fishman, J. and Hellman, L. 1973. J Clin Endocrinol Metab. 36: 160-4. PMID: 4681879
  9. Estradiol transformation in men with breast cancer.  |  Zumoff, B., et al. 1966. J Clin Endocrinol Metab. 26: 960-6. PMID: 5926948
  10. Metabolism of radioactive estrone and estradiol by the golden hamster.  |  Collins, DC., et al. 1967. Endocrinology. 80: 893-5. PMID: 6023557
  11. Some ring a methoxy-derivatives of estrone and estradiol-17-beta.  |  Conrow, RB., et al. 1967. Steroids. 9: 307-26. PMID: 6034607
  12. Plasma precursors of estrogen. I. Extent of conversion of plasma delta-4-androstenedione to estrone in normal males and nonpregnant normal, castrate and adrenalectomized females.  |  MacDonald, PC., et al. 1967. J Clin Endocrinol Metab. 27: 1103-11. PMID: 6035658
  13. Metabolism of estrone sulphate by benign prostatic hyperplasia in vitro.  |  Carlström, K., et al. 1980. Scand J Urol Nephrol. 14: 135-7. PMID: 6163200
  14. Separation of steroidal estrogens and their major unconjugated metabolites by high performance liquid chromatography.  |  Aten, RF., et al. 1982. J Steroid Biochem. 16: 447-9. PMID: 6283270
  15. Estrogen 2-, 4-, 6- or 16-hydroxylation by human follicles shown by gas chromatography-mass spectrometry associated with stable isotope dilution.  |  Dehennin, L., et al. 1984. J Steroid Biochem. 20: 465-71. PMID: 6708529

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Methoxy Estrone, 50 mg

sc-482856
50 mg
$416.00