Date published: 2026-1-13

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2-Iodoethanol (CAS 624-76-0)

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Alternate Names:
Ethylene iodohydrin
Application:
2-Iodoethanol is used in the synthesis of neuroexcitants
CAS Number:
624-76-0
Purity:
≥98%
Molecular Weight:
171.97
Molecular Formula:
C2H5IO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Iodoethanol is a versatile organic compound. This colorless, volatile liquid finds extensive use as a reagent in organic synthesis. It has played a role as a key reagent in organic synthesis and in the production of various chemicals such as 2-Iodoethanol glycol, 2-Iodoethanol oxide, and 2-Iodoethanol glycol ethers. The reactivity of 2-iodoethanol stems from its structure and the presence of a highly reactive iodine atom. This reactivity allows it to form covalent bonds with other molecules, thus facilitating its utilization as a catalyst in numerous chemical reactions.


2-Iodoethanol (CAS 624-76-0) References

  1. Polydentate N(2)S(2)O and N(2)S(2)O(2) Ligands as Alcoholic Derivatives of (N,N'-Bis(2-mercaptoethyl)-1,5-diazacyclooctane)nickel(II) and (N,N'-Bis(2-mercapto-2-methylpropane)-1,5-diazacyclooctane)nickel(II).  |  Goodman, DC., et al. 1996. Inorg Chem. 35: 4029-4037. PMID: 11666601
  2. The tetra(vinyl)phosphonium cation [(CH2=CH)4P]+.  |  Monkowius, UV., et al. 2004. J Am Chem Soc. 126: 1632-3. PMID: 14871084
  3. Synthesis of alpha-kainic acid from a 7-azabicyclo[2.2.1]heptadiene by tandem radical addition-homoallylic radical rearrangement.  |  Hodgson, DM., et al. 2005. Org Lett. 7: 815-7. PMID: 15727448
  4. Crotonaldehyde formation from decomposition of ICH2CH2OH on powdered TiO2.  |  Wu, WC., et al. 2006. J Phys Chem B. 110: 9627-31. PMID: 16686511
  5. Energetics of C-F, C-Cl, C-Br, and C-I bonds in 2-haloethanols. enthalpies of formation of XCH(2)CH(2)OH (X = F, Cl, Br, I) compounds and of the 2-hydroxyethyl radical.  |  Bernardes, CE., et al. 2007. J Phys Chem A. 111: 1713-20. PMID: 17288411
  6. Activation of the C-I and C-OH bonds of 2-iodoethanol by gas phase silver cluster cations yields subvalent silver-iodide and -hydroxide cluster cations.  |  Khairallah, GN. and O'Hair, RA. 2007. Dalton Trans. 3149-57. PMID: 17637990
  7. Photodissociation of 2-iodoethanol within the A band.  |  Shubert, VA., et al. 2009. J Phys Chem A. 113: 9057-64. PMID: 19610650
  8. DNA and RNA sequencing utilizing phosphorothioate chemistry.  |  Gish, G. and Eckstein, F. 1987. Nucleic Acids Symp Ser. 253-6. PMID: 2447567
  9. A novel route to C-unsubstituted 1,2-oxaphosphetane and 1,2-oxaphospholane complexes.  |  Kyri, AW., et al. 2016. Chem Commun (Camb). 52: 8593-5. PMID: 27320731
  10. Surface modification of pH-responsive poly(2-(tert-butylamino)ethyl methacrylate) brushes grafted on mesoporous silica nanoparticles.  |  Alswieleh, AM., et al. 2019. Des Monomers Polym. 22: 226-235. PMID: 31853240
  11. Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates.  |  Nakamaye, KL., et al. 1988. Nucleic Acids Res. 16: 9947-59. PMID: 3194230
  12. Synthesis of the Aminovinylcysteine-Containing C-Terminal Macrocycle of the Linaridins.  |  Lutz, JA. and Taylor, CM. 2020. Org Lett. 22: 1874-1877. PMID: 32043888
  13. Synergistic effect of intra- and intermolecular hydrogen bond in 2-haloethanols probed by infrared.  |  Martins, FA., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 288: 122205. PMID: 36473298
  14. Photocatalytic 2-Iodoethanol Coupling to Produce 1,4-Butanediol Mediated by TiO2 and a Catalytic Nickel Complex.  |  Xu, Q., et al. 2023. Angew Chem Int Ed Engl. e202301668. PMID: 37292043

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Iodoethanol, 5 g

sc-230429
5 g
$34.00