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2-Hydroxymethyl-18-crown-6 (CAS 70069-04-4)

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Alternate Names:
18-Crown-6-methanol, 1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanol
CAS Number:
70069-04-4
Molecular Weight:
294.34
Molecular Formula:
C13H26O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxymethyl-18-crown-6 has shown to be a fluorescence sensor for various metal ions, including zinc, copper, and nickel. Beyond this role, it finds utility within perovskite solar cells, contributing as a hole transporting material. This compound′s adaptability is highlighted through its capacity for modification with diverse substituents, each leading to distinct effects. Notably, fatty acid modifications has shown to enhance water solubility and influence degradation characteristics. The macrocyclic structure inherent to 2-Hydroxymethyl-18-crown-6 underpins its unique potential to selectively bind specific metal ions, forming a distinctive ′crown′ arrangement. This exceptional property equips crown ethers with multifaceted utility, spanning applications such as ion-exchange chromatography, metal ion separation, and the synthesis of coordination complexes.


2-Hydroxymethyl-18-crown-6 (CAS 70069-04-4) References

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  7. Development of effective potassium acetate extractant.  |  Zakrzewski, M., et al. 2021. RSC Adv. 11: 10860-10865. PMID: 35423584
  8. 2-Hydroxymethyl-18-crown-6 as an efficient organocatalyst for α-aminophosphonates synthesized under eco-friendly conditions, DFT, molecular docking and ADME/T studies.  |  Guezane-Lakoud, S., et al. 2023. J Biomol Struct Dyn. 1-17. PMID: 37184142
  9. Substitution‐reduction: an alternative process for the [18F] N‐(2‐fluoroethylation) of anilines  |  Briard, E., & Pike, V. W. 2004. Journal of Labelled Compounds and Radiopharmaceuticals. 47(4): 217-232.
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  11. Crown-ether functionalized fullerene as a solution-processable cathode buffer layer for high performance perovskite and polymer solar cells  |  Liu, X., Jiao, W., Lei, M., Zhou, Y., Song, B., & Li, Y. 2015. Journal of Materials Chemistry A. 3(17): 9278-9284.
  12. Heteroditopic receptor flexibility–an important design principle for effective ion pair extractants based on carboxylate studies  |  Zakrzewski, M., & Piątek, P. 2021. New Journal of Chemistry. 45(39): 18635-18640.
  13. Tritium Labeling and Phase Distribution of 18-Crown-6 and Its Derivatives for Further Reprocessing of Radium Waste  |  Kazakov, A. G., Ekatova, T. Y., Babenya, J. S., Vinokurov, S. E., & Badun, G. A. 2022. Energies. 15(19): 6867.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxymethyl-18-crown-6, 250 mg

sc-238087
250 mg
$70.00