Date published: 2026-5-11

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2-Hydroxymethyl-15-crown-5 (CAS 75507-25-4)

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Alternate Names:
1,4,7,10,13-Pentaoxacyclopentadecane-2-methanol
CAS Number:
75507-25-4
Molecular Weight:
250.29
Molecular Formula:
C11H22O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxymethyl-15-crown-5 functions as a complexing agent. It has a high affinity for alkali metal ions, particularly potassium, and forms stable complexes with them. The compound′s mechanism of action involves the formation of a cavity that can encapsulate the metal ion, leading to the formation of a stable complex. This complexation process is driven by the ability of the crown ether to coordinate with the metal ion through its oxygen atoms, resulting in the formation of a stable coordination complex. 2-Hydroxymethyl-15-Crown-5′s functional role lies in its ability to selectively bind to specific metal ions, which may be useful for various experimental applications where the selective complexation of alkali metal ions is required.


2-Hydroxymethyl-15-crown-5 (CAS 75507-25-4) References

  1. A cooperative effect of bifunctionalized nanoparticles on recognition: sensing alkali ions by crown and carboxylate moieties in aqueous media.  |  Lin, SY., et al. 2005. Anal Chem. 77: 4821-8. PMID: 16053294
  2. Synthesis, complexation, and fluorescence behavior of armed crown ethers carrying naphthyl group.  |  Kubo, K., et al. 1999. Talanta. 49: 735-44. PMID: 18967649
  3. Extraction and separation of a lysine-rich protein by formation of supramolecule between crown ether and protein in aqueous two-phase system.  |  Oshima, T., et al. 2010. Anal Chim Acta. 674: 211-9. PMID: 20678632
  4. Thermodynamic analysis of alkali metal complex formation of polymer-bonded crown ether.  |  Bey, A., et al. 2017. Phys Chem Chem Phys. 19: 15924-15932. PMID: 28589999
  5. Kinetic differences in the intercalation of linear and cyclic penta(ethylene oxide)s into graphite oxide leading to separation by topology.  |  Barroso-Bujans, F. and Alegria, A. 2017. Phys Chem Chem Phys. 19: 18366-18371. PMID: 28678232

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxymethyl-15-crown-5, 250 mg

sc-238086
250 mg
$111.00