2-Hydroxyisocaproic acid (CAS 498-36-2)
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2-Hydroxyisocaproic acid is a compound that functions as an inhibitor of branched-chain alpha-keto acid dehydrogenase kinase. It acts by reducing the phosphorylation of the branched-chain alpha-keto acid dehydrogenase complex, leading to an increase in its activity. 2-Hydroxyisocaproic acid plays a role in regulating the metabolism of branched-chain amino acids, leucine, isoleucine, and valine, by modulating the activity of the dehydrogenase complex. By inhibiting the kinase enzyme, 2-Hydroxyisocaproic acid promotes the decarboxylation of alpha-keto acids derived from branched-chain amino acids, ultimately affecting their catabolism. 2-Hydroxyisocaproic acid′s mode of action involves direct interaction with the kinase enzyme, leading to changes in the phosphorylation status of the dehydrogenase complex and subsequent effects on branched-chain amino acid metabolism.
2-Hydroxyisocaproic acid (CAS 498-36-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxyisocaproic acid, 1 g | sc-230410 | 1 g | $83.00 |