Date published: 2026-5-26

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2-Hydroxybenzophenone (CAS 117-99-7)

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Alternate Names:
2-Benzoylphenol
CAS Number:
117-99-7
Molecular Weight:
198.22
Molecular Formula:
HOC6H4COC6H5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxybenzophenone has found utility in the realm of organic chemistry as a valuable building block for synthesizing diverse organic compounds. Its versatile nature enables it to serve as a reactant in numerous chemical reactions. Moreover, scientists have investigated the potential of 2-Hydroxybenzophenone as useful in polymer synthesis and the creation of other materials.


2-Hydroxybenzophenone (CAS 117-99-7) References

  1. Photosensitizing properties of compounds related to benzophenone.  |  Placzek, M., et al. 2013. Acta Derm Venereol. 93: 30-2. PMID: 22983706
  2. Systematic study of the luminescent europium-based nonanuclear clusters with modified 2-hydroxybenzophenone ligands.  |  Zhang, B., et al. 2013. Inorg Chem. 52: 13332-40. PMID: 24224576
  3. A reevaluation of the photolytic properties of 2-hydroxybenzophenone-based UV sunscreens: are chemical sunscreens inoffensive?  |  Ignasiak, MT., et al. 2015. Chemphyschem. 16: 628-33. PMID: 25581220
  4. Physicochemical characterization of 2-hydroxybenzophenone with β-cyclodextrin in solution and solid state.  |  Sancho, MI., et al. 2015. J Phys Chem B. 119: 5918-25. PMID: 25893377
  5. Regioselective construction of diverse and multifunctionalized 2-hydroxybenzophenones for sun protection by indium(iii)-catalyzed benzannulation.  |  Cai, H., et al. 2016. Chem Commun (Camb). 52: 7661-4. PMID: 27126271
  6. 2-Hydroxybenzophenone as a Chemical Auxiliary for the Activation of Ketiminoesters for Highly Enantioselective Addition to Nitroalkenes under Bifunctional Catalysis.  |  Guerrero-Corella, A., et al. 2018. Angew Chem Int Ed Engl. 57: 5350-5354. PMID: 29493860
  7. Intramolecular hydrogen-bond activation for the addition of nucleophilic imines: 2-hydroxybenzophenone as a chemical auxiliary.  |  Choubane, H., et al. 2018. Chem Commun (Camb). 54: 3399-3402. PMID: 29557452
  8. Hydrogen-Bonding-Assisted Ketimine Formation of Benzophenone Derivatives.  |  Seo, MS., et al. 2018. J Org Chem. 83: 14300-14306. PMID: 30398053
  9. Transition-metal-free cascade benzannulations for synthesizing 2-hydroxybenzophenones.  |  He, XW., et al. 2020. Org Biomol Chem. 18: 9039-9043. PMID: 33141141
  10. Simultaneous trace analysis of 10 benzophenone-type ultraviolet filters in fish through liquid chromatography-tandem mass spectrometry.  |  Huang, YF., et al. 2021. Environ Pollut. 286: 117306. PMID: 33991738
  11. 2-Hydroxybenzophenone Derivatives: ESIPT Fluorophores Based on Switchable Intramolecular Hydrogen Bonds and Excitation Energy-Dependent Emission.  |  Wang, H., et al. 2021. Front Chem. 9: 766179. PMID: 34738006
  12. Cumulative Dietary Risk Assessment of Benzophenone-Type Photoinitiators from Packaged Foodstuffs.  |  Chen, ML., et al. 2022. Foods. 11: PMID: 35053884
  13. Identification of Benzophenone Analogs in Rice Cereal through Fast Pesticide Extraction and Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry.  |  Liu, XR., et al. 2022. Foods. 11: PMID: 35206047
  14. Rapid determination of benzophenone derivatives in cereals using FaPEx coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry.  |  Huang, YF., et al. 2021. J Food Drug Anal. 29: 287-302. PMID: 35696205
  15. The binding mechanism of benzophenone-type UV filters and human serum albumin: The role of site, number, and type of functional group substitutions.  |  Ma, J., et al. 2023. Environ Pollut. 324: 121342. PMID: 36828352

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxybenzophenone, 5 g

sc-223444
5 g
$51.00

2-Hydroxybenzophenone, 25 g

sc-223444A
25 g
$149.00