Date published: 2026-5-23

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2-Hydroxybenzaldehyde phenylhydrazone (CAS 614-65-3)

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Alternate Names:
Salicylic aldehyde phenylhydrazone
CAS Number:
614-65-3
Purity:
≥96%
Molecular Weight:
212.25
Molecular Formula:
C13H12N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxybenzaldehyde phenylhydrazone functions as a chelating agent in experimental applications. It has the ability to form stable complexes with metal ions, particularly transition metals such as copper and nickel. 2-Hydroxybenzaldehyde Phenylhydrazone acts by coordinating with the metal ions through its functional groups, forming a stable complex that can be utilized in various chemical and biochemical processes. At the molecular level, 2-Hydroxybenzaldehyde phenylhydrazone interacts with metal ions through its hydroxyl and hydrazone groups, leading to the formation of coordination complexes. These complexes can be utilized in experimental procedures such as metal ion detection, catalysis, and as intermediates in organic synthesis. 2-Hydroxybenzaldehyde phenylhydrazone′s mechanism of action involves its ability to selectively bind to metal ions, making it useful in various applications.


2-Hydroxybenzaldehyde phenylhydrazone (CAS 614-65-3) References

  1. Alkyldimethylpyrazines in the defensive spray of Phyllium westwoodii: a first for order Phasmatodea.  |  Dossey, AT., et al. 2009. J Chem Ecol. 35: 861-70. PMID: 19685263
  2. Synthesis of a cyclic pentapeptide mimic of the active site His-Tyr cofactor of cytochrome c oxidase.  |  Mahoney, ME., et al. 2009. J Org Chem. 74: 8212-8. PMID: 19810693
  3. Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.  |  Sieber, JD., et al. 2018. J Org Chem. 83: 1448-1461. PMID: 29323903
  4. Disposable cartridge concept for the on-demand synthesis of turbo Grignards, Knochel-Hauser amides, and magnesium alkoxides.  |  Berton, M., et al. 2020. Beilstein J Org Chem. 16: 1343-1356. PMID: 32595782
  5. Anisotropic Microgels by Supramolecular Assembly and Precipitation Polymerization of Pyrazole-Modified Monomers.  |  Grabowski, F., et al. 2022. Adv Sci (Weinh). 9: e2204853. PMID: 36310110
  6. Iron-Catalyzed Hydromagnesiation: Synthesis and Characterization of Benzylic Grignard Reagent Intermediate and Application in the Synthesis of Ibuprofen  |  Mark D. Greenhalgh, Adam Kolodziej, Fern Sinclair, and Stephen P. Thomas*. 2014,. Organometallics. 33, 20,: 5811–5819.
  7. P(n-Bu)3 Catalyzed Reactions of Salicyl N-Thiophosphinyl Imines with Allenylphosphonates: Synthesis of Phosphono-Chromans  |   and R. Rama Suresh, R. N. Prasad Tulichala, Ramesh Kotikalapudi, K. C. Kumara Swamy. May 2014. Journal of Heterocyclic Chemistry. Volume51, Issue3: Pages 760-767.
  8. Automated On-Demand Titration of Organometallic Reagents in Continuous Flow  |  Aaron A. Bedermann, T. Andrew McTeague, and Timothy F. Jamison*. 2019. Org. Process Res. Dev., 23, 2,: 278–282.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxybenzaldehyde phenylhydrazone, 5 g

sc-230399
5 g
$61.00