Date published: 2025-9-29

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2-Hydroxy Trimipramine (CAS 2064-15-5)

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Application:
2-Hydroxy Trimipramine is A Trimipramine metabolite
CAS Number:
2064-15-5
Purity:
98%
Molecular Weight:
310.43
Molecular Formula:
C20H26N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Hydroxy Trimipramine, a notable metabolite of Trimipramine, exhibits its unique characteristics through the specific interaction with dopamine receptors, which plays a pivotal role in the modulation of dopamine signaling pathways. This interaction is fundamental in research applications where understanding the intricacies of neurotransmitter dynamics is essential. By binding to these receptors, 2-Hydroxy Trimipramine serves as useful in the exploration of dopaminergic system functions, offering insights into the complex mechanisms governing neurotransmission.


2-Hydroxy Trimipramine (CAS 2064-15-5) References

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  2. Influence of quinidine on the pharmacokinetics of trimipramine and on its effect on the waking EEG of healthy volunteers. A pilot study on two subjects.  |  Eap, CB., et al. 1992. Neuropsychobiology. 25: 214-20. PMID: 1454163
  3. Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activity.  |  Kirchheiner, J., et al. 2003. Pharmacogenetics. 13: 721-8. PMID: 14646691
  4. The impact of the CYP2D6-polymorphism on dose recommendations for current antidepressants.  |  Thuerauf, N. and Lunkenheimer, J. 2006. Eur Arch Psychiatry Clin Neurosci. 256: 287-93. PMID: 16783493
  5. Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters.  |  Haenisch, B., et al. 2011. Psychopharmacology (Berl). 217: 289-95. PMID: 21484238
  6. Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants.  |  Eap, CB., et al. 2021. World J Biol Psychiatry. 22: 561-628. PMID: 33977870
  7. Determination of trimipramine and its demethylated and hydroxylated metabolites in plasma by gas chromatography-mass spectrometry.  |  Eap, CB., et al. 1994. J Chromatogr. 652: 97-103. PMID: 8014234
  8. Increased trimipramine plasma levels during fluvoxamine comedication.  |  Seifritz, E., et al. 1994. Eur Neuropsychopharmacol. 4: 15-20. PMID: 8204992
  9. Safety of liver donation after fatal intoxication with the tricyclic antidepressant trimipramine.  |  Fattinger, KE., et al. 1996. Transplantation. 62: 1259-62. PMID: 8932268
  10. Quantitation of trimipramine enantiomers in human serum by enantioselective high-performance liquid chromatography and mixed-mode disc solid-phase extraction.  |  Liu, J. and Stewart, JT. 1997. J Chromatogr B Biomed Sci Appl. 700: 175-82. PMID: 9390727

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Hydroxy Trimipramine, 1 mg

sc-206454
1 mg
$337.00

2-Hydroxy Trimipramine, 2 mg

sc-206454A
2 mg
$490.00

2-Hydroxy Trimipramine, 5 mg

sc-206454B
5 mg
$867.00