2-Hydroxy Atorvastatin-d5 Disodium Salt (CAS 1276537-19-9)
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2-Hydroxy Atorvastatin-d5 Disodium Salt is utilized in the study of lipid metabolism and the elucidation of pharmacokinetic profiles, specifically concerning its non-deuterated counterpart. As a deuterated compound, it serves as an important tool in mass spectrometry, offering a stable isotopic tracer that aids in distinguishing between the parent molecule and its metabolites during analysis. This compound is integral in research exploring the enzyme-substrate interactions within the metabolic pathways of statins. Environmental stability and the introduction of deuterium atoms ensure minimal isotopic effects, allowing for more accurate extrapolation of data to the non-deuterated analog. Moreover, 2-Hydroxy Atorvastatin-d5 Disodium Salt is used in the calibration of analytical instruments to improve the precision of detection and quantification in various biological matrices.
2-Hydroxy Atorvastatin-d5 Disodium Salt (CAS 1276537-19-9) References
- Microdosing Cocktail Assay Development for Drug-Drug Interaction Studies. | Chavez-Eng, CM., et al. 2018. J Pharm Sci. 107: 1973-1986. PMID: 29548977
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxy Atorvastatin-d5 Disodium Salt, 1 mg | sc-213819 | 1 mg | $500.00 | |||
2-Hydroxy Atorvastatin-d5 Disodium Salt, 1 mg | sc-213819-CW | 1 mg | $650.00 |