2-Hydroxy-3-isopropylbenzoic acid (CAS 7053-88-5)
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2-Hydroxy-3-isopropylbenzoic acid (2H3IPBA) is a carboxylic acid derived from benzoic acid. Its molecular structure consists of a benzene ring, where a hydroxyl group is attached to the C-2 position, and an isopropyl group is attached to the C-3 position. 2-Hydroxy-3-isopropylbenzoic acid finds extensive use in various endeavors. 2-Hydroxy-3-isopropylbenzoic acid serves as a substrate in enzyme assays and as a reagent in organic synthesis. Notably, it has been utilized for synthesizing diverse compounds, including agrochemicals and dyes. Investigations have focused on its potential as an inhibitor of cyclooxygenase-2 (COX-2), an enzyme of significance. It is hypothesized that the compound functions as an inhibitor of the enzyme cyclooxygenase-2 (COX-2). This particular enzyme plays a role in the synthesis of prostaglandins, hormones that contribute to inflammation and pain processes.
2-Hydroxy-3-isopropylbenzoic acid (CAS 7053-88-5) References
- General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility. | Krasowski, MD., et al. 2001. J Pharmacol Exp Ther. 297: 338-51. PMID: 11259561
- Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes. | Koljonen, M., et al. 2008. Eur J Pharm Biopharm. 70: 531-8. PMID: 18582575
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxy-3-isopropylbenzoic acid, 1 g | sc-230379 | 1 g | $51.00 |