Date published: 2026-3-29

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2-Fluoroethyl chloroformate (CAS 462-27-1)

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CAS Number:
462-27-1
Molecular Weight:
126.51
Molecular Formula:
ClCO2CH2CH2F
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Fluoroethyl chloroformate is an alkyl fluorinated building block. Used in the synthesis of potent and selective nonpeptide antagonist of melanocortin-4 receptor. Used as a reagent for the synthesis of peptides, antibiotics, and nucleotides. It can also be used as a protecting group for amino acids and peptides during complex organic structure synthesis.


2-Fluoroethyl chloroformate (CAS 462-27-1) References

  1. Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids.  |  Heise, T., et al. 2019. J Med Chem. 62: 1014-1021. PMID: 30543426
  2. Synthesis and Investigation of Organic Fluorine Compounds. XXII. The Preparation of Newer 2-Fluoroethylurethan Derivatives  |  Olah, G., Kuhn, S., & Kovacs-Bruckner, G. 1957. The Journal of Organic Chemistry. 22(8): 979-980.
  3. Synthesis from Thiolacetates. I. Synthesis of Alkanesulfonyl Chlorides  |  Bordwell, F., & Hewett, W. 1957. The Journal of Organic Chemistry. 22(8): 980-981.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Fluoroethyl chloroformate, 1 g

sc-230345
1 g
$94.00