Date published: 2026-4-29

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2-Fluoro-6-(trifluoromethyl)benzonitrile (CAS 133116-83-3)

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CAS Number:
133116-83-3
Molecular Weight:
189.11
Molecular Formula:
CF3C6H3(F)CN
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Fluoro-6-(trifluoromethyl)benzonitrile (2F6TBN) is an organic compound with fluorinated properties and is derived from benzonitrile, a common building block in organic synthesis. This versatile compound finds extensive use in various applications, serving as a valuable reactant for producing heterocyclic compounds and acting as a catalyst for diverse reactions. Additionally, 2-Fluoro-6-(trifluoromethyl)benzonitrile plays a role in synthesizing polymers and other materials. The widespread application of 2-Fluoro-6-(trifluoromethyl)benzonitrile in scientific research owes itself to its exceptional properties. Being polar, it forms hydrogen bonds with other molecules, which proves advantageous in catalyzing different reactions by facilitating the formation of new bonds between molecules. Moreover, its fluoroalkyl group serves as a substrate for other reactions, making it highly valuable as a reactant in organic synthesis.


2-Fluoro-6-(trifluoromethyl)benzonitrile (CAS 133116-83-3) References

  1. Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands.  |  Teng, H., et al. 2011. Bioorg Med Chem Lett. 21: 5999-6002. PMID: 21880487

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Fluoro-6-(trifluoromethyl)benzonitrile, 1 g

sc-225393
1 g
$41.00