Date published: 2025-12-18

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2-Ethylhexyl Salicylate (CAS 118-60-5)

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Alternate Names:
Salicylic Acid Octyl Ester
CAS Number:
118-60-5
Molecular Weight:
250.34
Molecular Formula:
C15H22O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Ethylhexyl Salicylate is a versatile compound widely used in various applications. It serves as an ester, formed by combining methoxycinnamic acid and 2-ethylhexanol. Primarily found in sunscreen products, this ingredient is highly valued for its broad-spectrum UV filtering capabilities, effectively absorbing both UVA and UVB rays. By harnessing its UV-absorbing properties, 2-Ethylhexyl Salicylate works to safeguard the skin from potential damage caused by harmful radiation. Apart from its role in sunscreens, 2-Ethylhexyl Salicylate plays a significant part in numerous personal care items, including lipsticks, moisturizers, and various cosmetics. Its usage is not limited to the realm of personal care, as it also finds application in industrial settings, where it contributes to the production of plasticizers and paint. The mechanism of 2-Ethylhexyl Salicylate revolves around absorbing ultraviolet radiation and converting it into harmless heat. 2-Ethylhexyl Salicylate stands as a multi-faceted compound, boasting UV-filtering prowess and showcasing potential. Its versatility and protective capabilities make it a valuable asset in the realm of industrial applications.


2-Ethylhexyl Salicylate (CAS 118-60-5) References

  1. Optical and electron paramagnetic resonance studies of the excited triplet states of UV-B absorbers: 2-ethylhexyl salicylate and homomenthyl salicylate.  |  Sugiyama, K., et al. 2015. Photochem Photobiol Sci. 14: 1651-9. PMID: 26135028
  2. New Hybrid Organic/Inorganic Polysilsesquioxane-Silica Particles as Sunscreens.  |  Tolbert, SH., et al. 2016. ACS Appl Mater Interfaces. 8: 3160-74. PMID: 26730573
  3. UV-filters and musk fragrances in seafood commercialized in Europe Union: Occurrence, risk and exposure assessment.  |  Cunha, SC., et al. 2018. Environ Res. 161: 399-408. PMID: 29197758
  4. Effects of steaming on contaminants of emerging concern levels in seafood.  |  Barbosa, V., et al. 2018. Food Chem Toxicol. 118: 490-504. PMID: 29787848
  5. Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS/MS.  |  Bury, D., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1110-1111: 59-66. PMID: 30780012
  6. Urinary metabolites of the UV filter 2-Ethylhexyl salicylate as biomarkers of exposure in humans.  |  Bury, D., et al. 2019. Toxicol Lett. 309: 35-41. PMID: 30953687
  7. A novel characteristic of salicylate UV absorbers: suppression of diethylhexyl 2,6-naphthalate (Corapan TQ)-photosensitized singlet oxygen generation.  |  Fukuchi, S., et al. 2019. Photochem Photobiol Sci. 18: 1556-1564. PMID: 31033968
  8. Quantification of prominent organic UV filters and their metabolites in human urine and plasma samples.  |  Klotz, K., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1125: 121706. PMID: 31302475
  9. Toxicokinetics of urinary 2-ethylhexyl salicylate and its metabolite 2-ethyl-hydroxyhexyl salicylate in humans after simulating real-life dermal sunscreen exposure.  |  Hiller, J., et al. 2019. Arch Toxicol. 93: 2565-2574. PMID: 31435713
  10. Occurrence and Gas-Particle Partitioning of Organic UV-Filters in Urban Air.  |  Pegoraro, CN., et al. 2020. Environ Sci Technol. 54: 12881-12889. PMID: 32924452
  11. Multi-analyte gas chromatography-mass spectrometry method to monitor bisphenols, musk fragrances, ultraviolet filters, and pesticide residues in seafood.  |  Petrarca, MH., et al. 2022. J Chromatogr A. 1663: 462755. PMID: 34968957
  12. Evaluation of the degradation capacity of WWTP sludge enrichment cultures towards several organic UV filters and the isolation of octocrylene-degrading microorganisms.  |  Fagervold, SK. and Lebaron, P. 2022. Sci Total Environ. 826: 154013. PMID: 35189223
  13. Synomones in necrophagous larvae of the blow flies Lucilia sericata and Calliphora vomitoria.  |  Fouche, Q., et al. 2023. Med Vet Entomol. 37: 170-175. PMID: 36196866
  14. Effect of ultraviolet-protective 2-ethylhexyl salicylate incorporation on the mechanical properties of different maxillofacial silicone elastomers.  |  Kılıçkaya, N., et al. 2023. J Prosthet Dent.. PMID: 36639255
  15. Effect of 2-ethylhexyl salicylate incorporation on the color stability of different maxillofacial silicone elastomers after outdoor weathering.  |  Bankoğlu Güngör, M., et al. 2023. J Prosthet Dent.. PMID: 37336678

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Ethylhexyl Salicylate, 25 ml

sc-474434
25 ml
$32.00

2-Ethylhexyl Salicylate, 500 ml

sc-474434A
500 ml
$108.00