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2-Ethyl-3-hydroxy-6-methylpyridine (CAS 2364-75-2)

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Alternate Names:
Emoxypine
CAS Number:
2364-75-2
Molecular Weight:
137.18
Molecular Formula:
C8H11NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Ethyl-3-hydroxy-6-methylpyridine is a compound of interest in synthetic organic chemistry, particularly due to the presence of both hydroxy and methyl functional groups on a pyridine ring. This structure provides a versatile platform for studying nucleophilic substitution reactions, where the pyridine ring can act as an electron-deficient target for various nucleophiles. In addition, the hydroxyl group in the 3-position makes it a candidate for studying the effects of intramolecular hydrogen bonding on the reactivity and stability of heteroaromatic compounds. Researchers also investigate the compound′s potential as a ligand in coordination chemistry, where the pyridine moiety can coordinate to transition metals, leading to the formation of complex structures with interesting catalytic and electronic properties. The ethyl and methyl substituents contribute to the lipophilicity of 2-Ethyl-3-hydroxy-6-methylpyridine, affecting its behavior in organic solvents and its interactions with other organic molecules, which is relevant for understanding the principles of molecular design and solute-solvent interactions.


2-Ethyl-3-hydroxy-6-methylpyridine (CAS 2364-75-2) References

  1. [Effect of mexidol, emoxypine, and dimephosphon on electrophysiological effects of nibentan].  |  Kotliarov, AA., et al. 2002. Eksp Klin Farmakol. 65: 27-30. PMID: 12109287
  2. [Effect of emoxypine on myocardial electrical instability and homeostasis parameters in patients with acute disturbance of cerebrovascular circulation].  |  Stoliarova, VV. 2002. Eksp Klin Farmakol. 65: 13-5. PMID: 12227086
  3. [Effects of antioxidant emoxipin on lipid metabolism in the lungs during development of pulmonary edema].  |  Mikhaĭlov, VP., et al. 1992. Biull Eksp Biol Med. 113: 139-41. PMID: 1611055
  4. [The effect of rubomycin, mexidol and emoxypine on some metabolic indexes and the proccess of spontaneous metastasis under conditions of experimental neoplasia].  |  Zor'kina, AV. and Prosvirina, ON. 2007. Eksp Klin Farmakol. 70: 57-9. PMID: 17402595
  5. Two polymorphs of 2-ethyl-3-hydroxy-6-methylpyridinium hydrogen N-acetyl-L-glutamate from powder diffraction data.  |  Chernyshev, VV., et al. 2013. Acta Crystallogr C. 69: 1549-52. PMID: 24311510
  6. [Anxiolytic and antidepressant effects of 3-oxypiridine and succinic acid derivatives in the acute phase of alloxan-induced diabetes in rats].  |  Volchegorskiĭ, IA., et al. 2014. Eksp Klin Farmakol. 77: 14-20. PMID: 25076754
  7. [Effect of magnesium, acetylsalicilic acid and emoxypine on aggregation of platelets].  |  Loznikova, SZh., et al. 2014. Biofizika. 59: 1108-12. PMID: 25715617
  8. [Anxiolytic and antidepressant effects of 3-oxypiridine and succinic acid derivatives in alloxan diabetes].  |  Volchegorskii, LA., et al. 2015. Ross Fiziol Zh Im I M Sechenova. 101: 258-67. PMID: 26016320
  9. Retinoprotective Effect of 2-Ethyl-3-hydroxy-6-methylpyridine Nicotinate.  |  Peresypkina, A., et al. 2020. Biology (Basel). 9: PMID: 32121045
  10. Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?  |  Skulachev, VP., et al. 2020. Aging (Albany NY). 12: 5566-5584. PMID: 32229707
  11. [The efficacy of antioxidant treatment with mexidol forte in 250 patients with chronic cerebral venous insufficiency].  |  Chukanova, EI., et al. 2021. Zh Nevrol Psikhiatr Im S S Korsakova. 121: 57-63. PMID: 33834719
  12. Promising effects of emoxypine and its succinate derivative in the management of various diseases-with insights on recent patent applications.  |  Gupta, DS., et al. 2022. Curr Res Pharmacol Drug Discov. 3: 100121. PMID: 35992374
  13. Mutagenicity of products obtained from a maltol-ammonia browning model system.  |  Shibamoto, T., et al. 1981. J Agric Food Chem. 29: 643-6. PMID: 7019285

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Ethyl-3-hydroxy-6-methylpyridine, 1 g

sc-259805
1 g
$42.00

2-Ethyl-3-hydroxy-6-methylpyridine, 5 g

sc-259805A
5 g
$124.00

2-Ethyl-3-hydroxy-6-methylpyridine, 25 g

sc-259805B
25 g
$300.00