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2-Ethyl-3-hydroxy-4H-pyran-4-one (CAS 4940-11-8)

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Alternate Names:
Ethyl maltol
CAS Number:
4940-11-8
Molecular Weight:
140.14
Molecular Formula:
C7H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Ethyl-3-hydroxy-4H-pyran-4-one is an organic compound that has attention in various fields of research due to its potential as a building block in organic synthesis. Its structure exhibits the capacity to engage in diverse chemical reactions, thereby serving as an intermediate in the synthesis of more complex organic molecules. In the field of materials science, this compound′s propensity to form chelates with metal ions is exploited to study metal-organic interactions, which are fundamental in the design of novel coordination compounds. Analytical chemists are interested in the compound′s role in colorimetric assays, as its ability to change color upon reaction with certain substances is useful in detecting the presence of specific ions or molecules. Additionally, its ring structure is a point of focus for researchers investigating ring-opening polymerization processes, which are critical for the production of new polymeric materials with desirable properties.


2-Ethyl-3-hydroxy-4H-pyran-4-one (CAS 4940-11-8) References

  1. Synthesis and evaluation of anticonvulsant and antimicrobial activities of 3-hydroxy-6-methyl-2-substituted 4h-pyran-4-one derivatives.  |  Aytemir, MD., et al. 2004. Arch Pharm (Weinheim). 337: 281-8. PMID: 15095421
  2. Quantitative determination of compounds in tobacco essential oils by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry.  |  Zhu, S., et al. 2005. J Chromatogr A. 1086: 107-14. PMID: 16130661
  3. New tungstenocenes containing 3-hydroxy-4-pyrone ligands: antiproliferative activity on HT-29 and MCF-7 cell lines and binding to human serum albumin studied by fluorescence spectroscopy and molecular modeling methods.  |  Domínguez-García, M., et al. 2013. J Biol Inorg Chem. 18: 195-209. PMID: 23212785
  4. Combined kinetic studies and computational analysis on kojic acid analogous as tyrosinase inhibitors.  |  Lima, CR., et al. 2014. Molecules. 19: 9591-605. PMID: 25004069
  5. Ethyl maltol enhances copper mediated cytotoxicity in lung epithelial cells.  |  Durrani, K., et al. 2021. Toxicol Appl Pharmacol. 410: 115354. PMID: 33271249
  6. Two Vanadium(V) Complexes Derived from Bromo and Chloro-Substituted Hydrazone Ligands: Syntheses, Crystal Structures and Antimicrobial Property.  |  Sun, ZQ., et al. 2020. Acta Chim Slov. 67: 1281-1289. PMID: 33533465
  7. Effect of the replacement of tripodal 4N donors by two 2N chelators on the redox and cytotoxic activity of maltolato and deferipronato containing Co(III) complexes.  |  Nagy, S., et al. 2021. J Inorg Biochem. 220: 111372. PMID: 33962134
  8. Synthesis and Anti-Oomycete Preliminary Mechanism of Sulfonate Derivatives of Ethyl Maltol.  |  Xing, P., et al. 2022. Chem Biodivers. 19: e202200255. PMID: 35560978
  9. Comparison of comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry and gas chromatography–mass spectrometry for the analysis of tobacco essential oils  |  Shukui Zhu a, Xin Lu b, Jun Xing a, Shaowen Zhang a, Hongwei Kong b, Guowang Xu b, Caiying Wu a. 2005. Analytica Chimica Acta. 545: 224-231.
  10. Multivariate Classification of Cherry Wines Based on Headspace Solid Phase Microextraction and Gas Chromatography-Mass Spectrometry of Volatile Compounds  |  Zuo-Bing Xiao, Ni Zhang, Yun-Wei Niu, Tao Feng, Huai-Xiang Tian, Jian-Cai Zhu. 2015. International Journal of Food Properties. 18: 1272-1287.
  11. Evaluation of usage three natural extracts applied to three commercial wood species against five common molds  |  Mohamed Z.M. Salem a, Yassin E. Zidan b, Nesrin M.N. El Hadidi b, Maisa M.A. Mansour b, Wael A.A. Abo Elgat c. 2016. International Biodeterioration & Biodegradation. 110: 206-226.
  12. Synthesis, characterization, crystal structures, and antibacterial activity of oxidovanadium(V) complexes with mixed ligands  |  X. Y. Qiu, S. J. Liu, J. X. Lei & Y. T. Ye. 2017. Russian Journal of Coordination Chemistry. 43: 396–403.
  13. Crystal Structure of Zinc(II) Complexes with 2-Ethyl-3-hydroxy-4H-pyran-4-thione and 2-Ethyl-3-hydroxy-4H-pyran-4-selenone  |  Takayuki Nishiguchi, Masayuki Yamashita, Yutaka Yoshikawa & Hiroyuki Yasui. 2019. Crystallography Reports. 64: 1099–1102.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Ethyl-3-hydroxy-4H-pyran-4-one, 25 g

sc-238029
25 g
$64.00