2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid (CAS 165190-25-0)

2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid, cataloged under CAS number 165190-25-0, is a structurally complex polyunsaturated fatty acid characterized by its unique configuration of double bonds at the 2nd, 8th, 11th, and 14th carbon positions, with a mix of both E (trans) and Z (cis) isomers. This molecule is particularly notable for its role in modulating cellular mechanisms through its involvement in the lipid signaling pathways. The spatial arrangement of its double bonds significantly affects the way it interacts with enzymes and receptors involved in the biosynthesis and breakdown of key signaling molecules like eicosanoids. In research environments, this fatty acid has been a focal point in studies aimed at deciphering the complex details of lipid signaling networks that govern cellular responses to various stimuli. It has been used to probe the effects of fatty acid structure on the activity and efficiency of enzymes such as cyclooxygenases and lipoxygenases, which are central to the pathway producing molecules that regulate cellular functions like inflammation and proliferation. Additionally, 2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid serves as a tool in ecological studies, contributing insights into how dietary fatty acids influence the lipid composition and adaptative mechanisms of different organisms, thereby offering a broader perspective on lipid functionality and adaptation in varying environmental contexts.