Molecular structure of 2-Dodecylcyclobutanone, CAS Number: 35493-46-0
2-Dodecylcyclobutanone (CAS 35493-46-0)
Application:
2-Dodecylcyclobutanone is a radiolytic product of fatty acids
CAS Number:
35493-46-0
Purity:
≥95%
Molecular Weight:
238.41
Molecular Formula:
C16H30O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
2-Dodecylcyclobutanone is formed when fat, particularly palmitic acid, is irradiated. It falls under the class of 2-alkylcyclobutanones which are under investigation as possible food contaminants. 2-Dodecylcyclobutanone has been found to be genotoxic in primary human colon cells.
2-Dodecylcyclobutanone (CAS 35493-46-0) References
- 2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions. | Knoll, N., et al. 2006. Mutat Res. 594: 10-9. PMID: 16153665
- Effect of cooking on radiation-induced chemical markers in beef and pork during storage. | Kwon, JH., et al. 2012. J Food Sci. 77: C211-5. PMID: 22225503
- Molecular mechanisms of apoptosis induction by 2-dodecylcyclobutanone, a radiolytic product of palmitic acid, in human lymphoma U937 cells. | Yu, DY., et al. 2012. Apoptosis. 17: 636-45. PMID: 22311471
- Rapid analysis of 2-alkylcyclobutanones in irradiated meats, cheese and salmon by direct solvent extraction followed by GPC. | Takahashi, K., et al. 2013. Shokuhin Eiseigaku Zasshi. 54: 173-7. PMID: 23863361
- Development of a competitive indirect enzyme-linked immunosorbent assay based on monoclonal antibodies for the detection of 2-dodecylcyclobutanone in irradiated beef. | Zhao, Y., et al. 2013. J Agric Food Chem. 61: 7749-53. PMID: 23875579
- Analysis of 2-alkylcyclobutanones in cashew nut, nutmeg, apricot kernel, and pine nut samples: re-evaluating the uniqueness of 2-alkylcyclobutanones for irradiated food identification. | Leung, EM., et al. 2013. J Agric Food Chem. 61: 9950-4. PMID: 24066811
- Methods of analysis for 2-dodecylcyclobutanone and studies to support its role as a unique marker of food irradiation. | Driffield, M., et al. 2014. Food Chem. 146: 308-13. PMID: 24176347
- Rapid identification of γ-irradiated food by direct solvent extraction and liquid chromatography-tandem mass spectrometric analysis of 2-dodecylcyclobutanone: application in surveillance of irradiated food. | Chan, W., et al. 2014. Food Chem. 161: 312-6. PMID: 24837955
- Genotoxic potential and in vitro tumour-promoting potential of 2-dodecylcyclobutanone and 2-tetradecylcyclobutanone, two radiolytic products of fatty acids. | Yamakage, K., et al. 2014. Mutat Res Genet Toxicol Environ Mutagen. 770: 95-104. PMID: 25344170
- Development of a novel biosensor based on F(0)F(1)-ATPase for the detection of 2-dodecylcyclobutanone in irradiated beef. | Zhao, Y., et al. 2015. Food Chem. 188: 320-4. PMID: 26041198
- Toxicological evaluation of 2-dodecylcyclobutanone, a unique radiolytic compound of palmitic acid. | Song, BS., et al. 2018. Food Chem Toxicol. 121: 639-647. PMID: 30268793
- Solid-phase micro extraction of food irradiation marker 2-dodecylcyclobutanone (2-DCB) from chicken jerky treated with glycerol. | Taghvaei, M., et al. 2020. J Food Sci. 85: 2608-2614. PMID: 32634283
- Interaction of 2-dodecylcyclobutanone (2-DCB) and internal standard in irradiated chicken jerkies and pig ears in solid-phase microextraction (SPME)-coupled gas chromatography-mass spectrometry (GC-MS) analysis. | Yucel, U., et al. 2023. Food Chem. 421: 136109. PMID: 37087992
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Dodecylcyclobutanone, 5 mg | sc-230254 | 5 mg | $165.00 |