Date published: 2025-9-25

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2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester

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Alternate Names:
1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
Application:
2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester is a Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules
Molecular Weight:
530.38
Molecular Formula:
C27H16F5O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester functions as a ligand. In the synthesis of metal-organic frameworks and coordination polymers. It acts as a chelating agent, forming stable complexes with transition metal ions through its phosphine and carboxylic acid groups. The presence of the methyl and pentafluorophenyl groups on the terephthalic acid backbone enhances the solubility and reactivity of the compound, making it suitable for various synthetic applications. In the context of research and development, this compound′s mode of action involves coordinating with metal ions to form coordination complexes, which can then be utilized in catalysis, sensing, or materials science. The diester functionality of the compound also provides opportunities for further derivatization, allowing for the introduction of additional functional groups to tailor its properties for specific applications. 2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester plays a crucial role in the design and synthesis of novel materials and catalysts, contributing to the advancement of various fields within the chemical sciences.


2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester References

  1. Long-term survival of allograft murine islets coated via covalently stabilized polymers.  |  Rengifo, HR., et al. 2014. Adv Healthc Mater. 3: 1061-70. PMID: 24497465
  2. Smart tools and orthogonal click-like reactions onto small unilamellar vesicles: Additional molecular data.  |  Vittoria Spanedda, M., et al. 2015. Data Brief. 5: 145-54. PMID: 26501083
  3. Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation.  |  Madl, CM., et al. 2016. Adv Funct Mater. 26: 3612-3620. PMID: 27642274
  4. Synthesis of a Highly Azide-Reactive and Thermosensitive Biofunctional Reagent for Efficient Enrichment and Large-Scale Identification of O-GlcNAc Proteins by Mass Spectrometry.  |  Zhang, W., et al. 2017. Anal Chem. 89: 5810-5817. PMID: 28510447
  5. Promoting Dendrimer Self-Assembly Enhances Covalent Layer-by-Layer Encapsulation of Pancreatic Islets.  |  Gattás-Asfura, KM., et al. 2020. ACS Biomater Sci Eng. 6: 2641-2651. PMID: 32587885

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester, 25 mg

sc-287614
25 mg
$109.00