Date published: 2026-4-29

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2-Diphenylmethylpiperidine (CAS 519-74-4)

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CAS Number:
519-74-4
Molecular Weight:
251.37
Molecular Formula:
C18H21N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Diphenylmethylpiperidine is an organic compound consisting of a piperidine ring substituted with a diphenylmethyl group. This compound is of interest in the field of organic chemistry, particularly in studies related to synthetic organic methodologies and the synthesis of novel organic molecules. It serves as a scaffold for the development of potential ligands due to the structural rigidity imparted by the diphenylmethyl group and the versatility of the piperidine moiety. In research focused on the design of new chemical entities, 2-Diphenylmethylpiperidine is often modified through various functional group transformations to explore its reactivity and to develop compounds with potential applications in material science or as intermediates for more complex chemical syntheses. The study of its chemical properties, including basicity and steric effects, provides valuable insight into the behavior of heterocyclic compounds under different reaction conditions. Additionally, as a secondary amine, 2-Diphenylmethylpiperidine is investigated for its ability to act as a catalyst or as a building block in the construction of supramolecular architectures.


2-Diphenylmethylpiperidine (CAS 519-74-4) References

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  2. Prevalence and blood concentrations of desoxypipradrol (2-DPMP) in drivers suspected of driving under the influence of drugs and in post-mortem cases.  |  Kriikku, P., et al. 2013. Forensic Sci Int. 226: 146-51. PMID: 23333504
  3. Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives.  |  Simmler, LD., et al. 2014. Biochem Pharmacol. 88: 237-44. PMID: 24486525
  4. Using poisons information service data to assess the acute harms associated with novel psychoactive substances.  |  Wood, DM., et al. 2014. Drug Test Anal. 6: 850-60. PMID: 24832864
  5. Investigation of drug products received for analysis in the Swedish STRIDA project on new psychoactive substances.  |  Bäckberg, M., et al. 2018. Drug Test Anal. 10: 340-349. PMID: 28600832
  6. Isomeric specificity of diphenylmethylpiperidine in the production of rat pancreatic islet cell toxicity.  |  Hintze, KL., et al. 1977. Toxicology. 7: 133-40. PMID: 324024
  7. The Role of Dopamine in the Stimulant Characteristics of Novel Psychoactive Substances (NPS)-Neurobiological and Computational Assessment Using the Case of Desoxypipradrol (2-DPMP).  |  Loi, B., et al. 2020. Front Pharmacol. 11: 806. PMID: 32670057
  8. Molecular mechanisms of action of stimulant novel psychoactive substances that target the high-affinity transporter for dopamine.  |  Sahai, MA. and Opacka-Juffry, J. 2021. Neuronal Signal. 5: NS20210006. PMID: 34888062

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Diphenylmethylpiperidine, 5 mg

sc-492220A
5 mg
$110.00

2-Diphenylmethylpiperidine, 25 mg

sc-492220B
25 mg
$439.00

2-Diphenylmethylpiperidine, 100 mg

sc-492220
100 mg
$612.00

2-Diphenylmethylpiperidine, 1 g

sc-492220C
1 g
$3742.00

2-Diphenylmethylpiperidine, 5 g

sc-492220D
5 g
$13770.00

2-Diphenylmethylpiperidine, 10 g

sc-492220E
10 g
$21410.00