Date published: 2026-2-16

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2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl (CAS 657408-07-6)

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Alternate Names:
2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl, S Phos, SPhos
CAS Number:
657408-07-6
Purity:
≥99%
Molecular Weight:
410.53
Molecular Formula:
C26H35O2P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl is a ligand functioning within the transition metal-catalyzed reactions. It functions as a bidentate ligand, coordinating to metal centers to facilitate various catalytic processes. The phosphine moiety of the compound interacts with transition metals, forming stable complexes that can participate in a range of catalytic transformations. 2-Dicyclohexylphosphino-2′,6′-Dimethoxybiphenyl′s mechanism of action involves coordinating with transition metals to modulate their reactivity, allowing for the selective formation of desired products in transformations. By serving as a ligand, 2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl plays a role in controlling the stereochemistry and regioselectivity of metal-catalyzed reactions, contributing to the development of efficient and selective methodologies. Its ability to influence the reactivity of transition metal complexes may be a function in the development of new chemical transformations and the synthesis of complex organic molecules.


2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl (CAS 657408-07-6) References

  1. A rationally designed universal catalyst for Suzuki-Miyaura coupling processes.  |  Walker, SD., et al. 2004. Angew Chem Int Ed Engl. 43: 1871-6. PMID: 15054800
  2. Evidence for the formation and structure of palladacycles during Pd-catalyzed C-N bond formation with catalysts derived from bulky monophosphinobiaryl ligands.  |  Strieter, ER. and Buchwald, SL. 2006. Angew Chem Int Ed Engl. 45: 925-8. PMID: 16381052

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl, 1 g

sc-256134
1 g
$69.00

2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl, 5 g

sc-256134A
5 g
$310.00