2-Deoxystreptamine, Dihydrobromide (CAS 2037-48-1)

2-Deoxystreptamine, Dihydrobromide acts as a structural core within the molecular framework of various aminocyclitol antibiotics, providing a foundational scaffold that is essential for the antibacterial activity of these compounds. Its presence is pivotal in the formation of complex molecular structures that interact with bacterial ribosomal RNA, thereby disrupting protein synthesis. This interaction specifically impedes the correct positioning of tRNA on the ribosome, a critical step in the translation process, leading to the inhibition of bacterial growth and proliferation. The mechanism of action of 2-Deoxystreptamine, Dihydrobromide, and its derivatives emphasizes its significance in research focused on understanding the nuances of bacterial resistance and the development of novel antibiotics. By studying this compound, researchers can gain insights into the structural requirements for antibacterial activity, paving the way for the synthesis of new antibiotics with enhanced efficacy against resistant bacterial strains.