Date published: 2025-12-29

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2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (CAS 141846-57-3)

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Application:
CAS Number:
141846-57-3
Molecular Weight:
388.84
Molecular Formula:
C21H21ClO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl chloride is a significant compound in carbohydrate chemistry research, primarily utilized as a glycosyl donor for the synthesis of various oligosaccharides and glycoconjugates. The mechanism of action of this chemical involves its reactivity as a glycosyl chloride, enabling it to undergo glycosylation reactions with acceptor molecules, typically hydroxyl-containing compounds, under suitable reaction conditions. Researchers exploit its reactivity to introduce the α-L-ribofuranosyl moiety into diverse carbohydrate structures, allowing for the creation of complex glycan motifs. Moreover, 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl chloride serves as a valuable tool in the study of carbohydrate-protein interactions and glycan-mediated processes. By synthesizing specific oligosaccharides using this compound as a glycosyl donor, scientists can investigate the role of carbohydrates in biological recognition events, such as cell adhesion, signaling, and pathogen-host interactions. Additionally, this chemical finds applications in the development of carbohydrate-based materials and biomimetic systems for various research purposes, including drug delivery, tissue engineering, and diagnostics. Its versatility as a glycosylation reagent and its compatibility with different synthetic methodologies make it a crucial component in the synthesis of carbohydrate derivatives and the exploration of carbohydrate biology. Through innovative research approaches, scientists continue to uncover new insights into the diverse roles of carbohydrates in biological systems, facilitated in part by the use of compounds like 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl chloride.


2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (CAS 141846-57-3) References

  1. Development of a Novel Synthetic Process for 2-Deoxy-3,5-di-O-p-toluoyl-α-l-ribofuranosyl Chloride:  A Versatile Intermediate in the Synthesis of 2'-Deoxy-l-ribonucleosides  |  Narayan C. Chaudhuri, Adel Moussa, Alistair Stewart, Jingyang Wang, and Richard Storer. 2005. Organic Process Research & Development. 9: 457–465.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride, 250 mg

sc-220732
250 mg
$180.00

2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride, 500 mg

sc-220732A
500 mg
$309.00

2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride, 1 g

sc-220732B
1 g
$510.00

2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride, 2.5 g

sc-220732C
2.5 g
$945.00