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2-Deoxy-2-fluoro-D-mannose (CAS 38440-79-8)

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CAS Number:
38440-79-8
Molecular Weight:
182.15
Molecular Formula:
C6H11FO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Deoxy-2-fluoro-D-mannose is a monosaccharide analogue that is utilized in biochemical research for its unique structural properties. This compound is particularly interesting to researchers studying glycosylation processes, as the fluorine atom can act as a mimic for the hydroxyl group that is normally present in D-mannose, offering insights into enzyme specificity and mechanism. Studies involving 2-Deoxy-2-fluoro-D-mannose are also relevant for exploring the stability and conformational dynamics of glycosidic bonds in various biological applications. In the field of synthetic chemistry, this compound serves as a building block for the preparation of complex oligosaccharides, potentially influencing the development of new materials with specific biological functions. Furthermore, research on this sugar analogue contributes to a greater understanding of carbohydrate-protein interactions, which are critical in many biological processes, including cell signaling and adhesion.


2-Deoxy-2-fluoro-D-mannose (CAS 38440-79-8) References

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  2. Fluorosugars inhibit biological properties of different enveloped viruses.  |  Schmidt, MF., et al. 1976. J Virol. 18: 819-23. PMID: 178923
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  6. Synthesis and purification of 2-deoxy-2-[18F]fluoro-D-glucose and 2-deoxy-2-[18F]fluoro-D-mannose: characterization of products by 1H- and 19F-NMR spectroscopy.  |  Oberdorfer, F., et al. 1986. Int J Rad Appl Instrum A. 37: 695-701. PMID: 3021670
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  9. Metabolism of 2-deoxy-2-fluoro-D-[3H]glucose and 2-deoxy-2-fluoro-D-[3H]mannose in yeast and chick-embryo cells.  |  Schmidt, MF., et al. 1978. Eur J Biochem. 87: 55-68. PMID: 352691
  10. NMR evidence for the unexpected interconversion of 2-deoxy-2-fluoro-D-glucose and 2-deoxy-2-fluoro-D-mannose in mice.  |  Kanazawa, Y., et al. 1987. Chem Pharm Bull (Tokyo). 35: 895-7. PMID: 3594701
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Deoxy-2-fluoro-D-mannose, 10 mg

sc-220726
10 mg
$286.00

2-Deoxy-2-fluoro-D-mannose, 100 mg

sc-220726A
100 mg
$843.00

2-Deoxy-2-fluoro-D-mannose, 1 g

sc-220726B
1 g
$5212.00