Molecular structure of 2-Deoxy-2-fluoro-D-glucose, CAS Number: 29702-43-0
2-Deoxy-2-fluoro-D-glucose (CAS 29702-43-0)
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Alternate Names:
2-Deoxy-2-fluoro-D-glucose is also known as FDG.
Application:
2-Deoxy-2-fluoro-D-glucose is a cellular glycosylation inhibitor.
CAS Number:
29702-43-0
Molecular Weight:
182.15
Molecular Formula:
C6H11FO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Deoxy-2-fluoro-D-glucose is a glucose analog that does not undergo metabolic glycolysis. 2-Deoxy-2-fluoro-D-glucose is a substrate of hexokinase isozymes. Additionally, it is an inhibitor of cellular glycosylation.
2-Deoxy-2-fluoro-D-glucose (CAS 29702-43-0) References
- History of the first synthesis of 2-deoxy-2-fluoro-D-glucose the unlabeled forerunner of 2-deoxy-2-[18F]fluoro-D-glucose. | Pacák, J. and Cerný, M. 2002. Mol Imaging Biol. 4: 352-4. PMID: 14537109
- Retinoblastoma treatment: utilization of the glycolytic inhibitor, 2-deoxy-2-fluoro-D-glucose (2-FG), to target the chemoresistant hypoxic regions in LH(BETA)T(AG) retinal tumors. | Piña, Y., et al. 2012. Invest Ophthalmol Vis Sci. 53: 996-1002. PMID: 22266512
- Distribution of 2-deoxy-2-fluoro-d-glucose in the coelom of healthy bald eagles (Haliaeetus leucocephalus). | Jones, MP., et al. 2013. Am J Vet Res. 74: 426-32. PMID: 23438118
- 2-Deoxy-2-fluoro-d-glucose metabolism in Arabidopsis thaliana. | Fatangare, A., et al. 2015. Front Plant Sci. 6: 935. PMID: 26579178
- Applications of 2-deoxy-2-fluoro-D-glucose (FDG) in Plant Imaging: Past, Present, and Future. | Fatangare, A. and Svatoš, A. 2016. Front Plant Sci. 7: 483. PMID: 27242806
- Positron Emission Tomography Fluorine-18-Labeled 2-Deoxy-2-Fluoro-d-Glucose Tells a Complicated Story in the Aortic Aneurysm Wall. | Curci, JA. and Beckman, JA. 2016. Circ Cardiovasc Imaging. 9: PMID: 27903546
- Non-radioactive 2-deoxy-2-fluoro-D-glucose inhibits glucose uptake in xenograft tumours and sensitizes HeLa cells to doxorubicin in vitro. | Niccoli, S., et al. 2017. PLoS One. 12: e0187584. PMID: 29095925
- Metabolic pathway of 2-deoxy-2-fluoro-D-glucose studied by F-19 NMR. | Kanazawa, Y., et al. 1986. Life Sci. 39: 737-42. PMID: 3736344
- A short synthesis of 2-deoxy-2-fluoro-D-glucose. | Kovác, P. 1986. Carbohydr Res. 153: 168-70. PMID: 3779690
- Lysis of Saccharomyces cerevisiae with 2-deoxy-2-fluoro-D-glucose, an inhibitor of the cell wall glucan synthesis. | Biely, P., et al. 1973. J Bacteriol. 115: 1108-20. PMID: 4580558
- A comparison of the toxic effects of 2-deoxy-D-glucose and 2-deoxy-2-fluoro-D-hexoses on Saccharomyces cerevisiae cells and protoplasts. | Biely, P., et al. 1981. Z Allg Mikrobiol. 21: 489-97. PMID: 7034385
- 2-Deoxy-2-fluoro-D-glucose as a functional probe for NMR: the unique metabolism beyond its 6-phosphate. | Kanazawa, Y., et al. 1996. J Neurochem. 66: 2113-20. PMID: 8780043
- 19F NMR of 2-deoxy-2-fluoro-D-glucose for tumor diagnosis in mice. An NDP-bound hexose analog as a new NMR target for imaging. | Kanazawa, Y., et al. 1997. NMR Biomed. 10: 35-41. PMID: 9251114
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Mpi.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Deoxy-2-fluoro-D-glucose, 25 mg | sc-220725A | 25 mg | $162.00 | |||
2-Deoxy-2-fluoro-D-glucose, 50 mg | sc-220725 | 50 mg | $293.00 | |||
2-Deoxy-2-fluoro-D-glucose, 100 mg | sc-220725B | 100 mg | $360.00 | |||
2-Deoxy-2-fluoro-D-glucose, 250 mg | sc-220725C | 250 mg | $734.00 | |||
2-Deoxy-2-fluoro-D-glucose, 500 mg | sc-220725D | 500 mg | $1359.00 |