Molecular structure of 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate, CAS Number: 143157-22-6
2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate (CAS 143157-22-6)
Alternate Names:
3,5-Di-O-benzoyl-2,2-difluoro-2-deoxyribose
Application:
2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate is an intermediate of the cytotoxic compound gemcitabine
CAS Number:
143157-22-6
Molecular Weight:
378.32
Molecular Formula:
C19H16F2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A Gemcitabine intermediate.
2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate (CAS 143157-22-6) References
- Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV. | Marquez, VE., et al. 1990. J Med Chem. 33: 978-85. PMID: 2106581
- Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine). | Hertel, LW., et al. 1990. Cancer Res. 50: 4417-22. PMID: 2364394
- Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. | Balzarini, J., et al. 1988. Biochem Pharmacol. 37: 2847-56. PMID: 2840080
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate, 100 mg | sc-220731 | 100 mg | $290.00 |