Date published: 2026-4-26

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2-Cyano-L-phenylalanine (CAS 263396-42-5)

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Alternate Names:
L-Phe(2-CN)-OH
CAS Number:
263396-42-5
Molecular Weight:
190.2
Molecular Formula:
C10H10N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Cyano-L-phenylalanine (L-2-CPA) is a non-proteinogenic amino acid derivative. Researchers have utilized 2-Cyano-L-phenylalanine in studies to investigate the mechanisms of action of various drugs, such as anticonvulsants and analgesics. Additionally, it has been used in studies of enzyme inhibition and protein-ligand binding, due to its ability to interact with multiple enzymes and proteins. Monoamine oxidase is one such enzyme that 2-Cyano-L-phenylalanine may act to inhibit, which is involved in the metabolism of neurotransmitters like serotonin and dopamine.


2-Cyano-L-phenylalanine (CAS 263396-42-5) References

  1. Comparison of biological chromophores: photophysical properties of cyanophenylalanine derivatives.  |  Martin, JP., et al. 2016. Phys Chem Chem Phys. 18: 20750-7. PMID: 27412819
  2. Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds.  |  der Poorten, OV., et al. 2018. Med Chem. 14: 400-408. PMID: 28969573

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Cyano-L-phenylalanine, 1 g

sc-288078
1 g
$316.00

2-Cyano-L-phenylalanine, 5 g

sc-288078A
5 g
$1312.00