2-Chloroquinoline-3-carboxylic acid (CAS 73776-25-7)
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2-Chloroquinoline-3-carboxylic acid finds extensive utility in a wide range of scientific research endeavors. Notably, it exhibits remarkable potency as an inhibitor of multiple enzymes, encompassing phospholipase A2, cyclooxygenase-2, and 5-lipoxygenase. Its application extends to unraveling the intricate structure and function of these enzymes, along with delving into the role of reactive oxygen species within cellular signaling pathways. By effectively binding to the active sites of these enzymes, 2-Chloroquinoline-3-carboxylic acid thwarts their catalytic potential, thereby impeding the reactions they typically facilitate. Such inhibition of enzymatic activity entails various downstream consequences, including the suppression of inflammatory pathways and the modulation of cell proliferation and apoptosis.
2-Chloroquinoline-3-carboxylic acid (CAS 73776-25-7) References
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- Synthesis, in silico molecular docking analysis, pharmacokinetic properties and evaluation of antibacterial and antioxidant activities of fluoroquinolines. | Fekadu, M., et al. 2022. BMC Chem. 16: 1. PMID: 35027086
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Chloroquinoline-3-carboxylic acid, 1 g | sc-251736 | 1 g | $64.00 |