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2-Chloroinosine (CAS 13276-43-2)

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Alternate Names:
2-CIDO
Application:
2-Chloroinosine is a halogenated nucleoside
CAS Number:
13276-43-2
Molecular Weight:
302.67
Molecular Formula:
C10H11ClN4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A Halogenated nucleoside.


2-Chloroinosine (CAS 13276-43-2) References

  1. Determination of lodenosine and its major metabolite in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry.  |  Roth, JS., et al. 2000. J Mass Spectrom. 35: 1313-9. PMID: 11114090
  2. Formation of 2-chloroinosine from guanosine by treatment of HNO(2) in the presence of NaCl.  |  Suzuki, T., et al. 2001. Bioorg Med Chem. 9: 2937-41. PMID: 11597475
  3. Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography; Identification of a novel metabolite of 2-chlorodeoxyadenosine.  |  Bierau, J., et al. 2004. J Chromatogr B Analyt Technol Biomed Life Sci. 805: 339-46. PMID: 15135110
  4. (15)N Double-labeled guanosine from inosine through ring-opening-ring-closing and one-pot Pd-catalyzed C-O and C-N cross-coupling reactions.  |  Caner, J. and Vilarrasa, J. 2010. J Org Chem. 75: 4880-3. PMID: 20550202
  5. Studies on adenosine deaminase. 2. Specificity and mechanism of action of bovine placental adenosine deaminase.  |  Maguire, MH. and Sim, MK. 1971. Eur J Biochem. 23: 22-9. PMID: 5127387
  6. Purine nucleosides. 8. The synthesis of 2-fluoro- and 2-chloroinosine and certain derived purine nucleosides.  |  Gerster, JF. and Robins, RK. 1966. J Org Chem. 31: 3258-62. PMID: 5917472
  7. Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.  |  Antonino, LC. and Wu, JC. 1994. Biochemistry. 33: 1753-9. PMID: 7906542
  8. N2-amination of guanine to 2-hydrazinohypoxanthine, a novel in vivo nucleic acid modification produced by the hepatocarcinogen 2-nitropropane.  |  Sodum, RS. and Fiala, ES. 1998. Chem Res Toxicol. 11: 1453-9. PMID: 9860487
  9. Synthesis of 2′‐deoxyguanosine containing a N2‐polyamine  |  Ramasamy, K. S., Bakir, F., Baker, B., & Dan Cook, P. 1993. Journal of heterocyclic chemistry. 30(5): 1373-1377.
  10. Reaction of NO with Nucleic Acid Bases and its Biological Implication  |  Pack, S. P., Suzuki, T., Ide, H., Kodaki, T., & Makino, K. 2005. Frontiers in Organic Chemistry. 1(1): 297-341.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloroinosine, 100 mg

sc-220721
100 mg
$280.00