Date published: 2026-4-27

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2-Chloroethyl ethyl sulfide (CAS 693-07-2)

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Alternate Names:
1-Chloro-2-ethylsulfanylethane
CAS Number:
693-07-2
Purity:
≥97%
Molecular Weight:
124.63
Molecular Formula:
C4H9ClS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloroethyl ethyl sulfide, referred to as CEES, is an important chemical compound with the molecular formula C4H9ClS. It exists as a colorless liquid with a distinct pungent odor. 2-Chloroethyl ethyl sulfide finds diverse applications in the scientific research, medical, industrial, and agricultural fields. Its use has contributed to the exploration of sulfur-containing compounds′ effects on cell membranes and enzyme activities. The mechanism by which 2-Chloroethyl ethyl sulfide operates is intricate and not yet fully comprehended. It is hypothesized that the compound interacts with proteins and other molecules within the cell membrane, resulting in alterations to their structure and function. Additionally, it is believed to engage with enzymes and other proteins participating in signal transduction pathways, subsequently influencing gene expression.


2-Chloroethyl ethyl sulfide (CAS 693-07-2) References

  1. Photocatalytic oxidation of gaseous 2-chloroethyl ethyl sulfide over TiO2.  |  Martyanov, IN. and Klabunde, KJ. 2003. Environ Sci Technol. 37: 3448-53. PMID: 12966994
  2. 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.  |  Jain, AK., et al. 2011. Toxicology. 282: 129-38. PMID: 21295104
  3. Biosynthesis and urinary excretion of methyl sulfonium derivatives of the sulfur mustard analog, 2-chloroethyl ethyl sulfide, and other thioethers.  |  Mozier, NM. and Hoffman, JL. 1990. FASEB J. 4: 3329-33. PMID: 2253846
  4. The chemiluminescence determination of 2-chloroethyl ethyl sulfide using luminol-AgNO3-silver nanoparticles system.  |  Maddah, B., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 142: 220-5. PMID: 25703367
  5. Decomposition of the Simulant 2-Chloroethyl Ethyl Sulfide Blister Agent under Ambient Conditions Using Metal-Organic Frameworks.  |  Kim, HH., et al. 2021. ACS Appl Mater Interfaces. 13: 3782-3792. PMID: 33461292
  6. Facile and rapid synthesis of functionalized Zr-BTC for the optical detection of the blistering agent simulant 2-chloroethyl ethyl sulfide (CEES).  |  Abuzalat, O., et al. 2021. Dalton Trans. 50: 3261-3268. PMID: 33586726
  7. Efficient solar light facilitated photo-oxidative detoxification of gaseous 2-chloroethyl ethyl sulfide on ZrO2-doped g-C3N4 under dry and humid air.  |  Tayyab, M., et al. 2021. Chemosphere. 280: 130685. PMID: 33951582
  8. Alterations in Mitochondrial and Inflammasome Homeostasis by 2-Chloroethyl Ethyl Sulfide and Their Mitigation by Curcumin: An in Vitro Study.  |  Kia, A., et al. 2021. Iran J Allergy Asthma Immunol. 20: 614-622. PMID: 34664820
  9. Decontamination of 2-Chloroethyl ethyl sulfide on the surface by atmospheric pressure plasma jet.  |  Li, Y., et al. 2022. J Hazard Mater. 424: 127536. PMID: 34879527
  10. Screening of the chemoprotective effect of 13 compounds and their mixtures with sodium 2-mercaptoethanesulfonate against 2-chloroethyl ethyl sulfide.  |  Jost, P., et al. 2019. J Appl Biomed. 17: 136-145. PMID: 34907735
  11. Surface- and Structural-Dependent Reactivity of Titanium Oxide Nanostructures with 2-Chloroethyl Ethyl Sulfide under Ambient Conditions.  |  Giles, SL., et al. 2022. ACS Appl Mater Interfaces. 14: 9655-9666. PMID: 35134290
  12. Enhancing the quantum yield of singlet oxygen: photocatalytic degradation of mustard gas simulant 2-chloroethyl ethyl sulfide catalyzed by a hybrid of polyhydroxyl aluminum cations and porphyrin anions.  |  Yang, Y., et al. 2022. RSC Adv. 12: 20251-20258. PMID: 35919596
  13. Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized human bronchial epithelial cells.  |  Ye, F., et al. 2022. Toxicol Mech Methods. 1-8. PMID: 36106344

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloroethyl ethyl sulfide, 5 g

sc-230213
5 g
$94.00