Date published: 2025-12-15

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2-Chlorobutyryl chloride (CAS 7623-11-2)

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Alternate Names:
Butanoyl chloride
Application:
2-Chlorobutyryl chloride is an acid halide for synthesis and proteomics research
CAS Number:
7623-11-2
Purity:
≥85%
Molecular Weight:
141.00
Molecular Formula:
C4H6Cl2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chlorobutyryl chloride is a chemical compound that functions as an acylating agent in organic synthesis. It is used to introduce the 2-chlorobutyryl group into various organic molecules, allowing for the modification of their chemical properties. The mechanism of action of 2-Chlorobutyryl chloride involves the substitution of the hydroxyl group in organic compounds with the 2-chlorobutyryl group, leading to the formation of new chemical bonds. 2-Chlorobutyryl Chloride reaction occurs through nucleophilic acyl substitution, where the chlorine atom in 2-Chlorobutyryl chloride is replaced by the hydroxyl group of the organic molecule, resulting in the formation of an acylated product. This process is used in the synthesis agrochemicals, enabling the production of diverse chemical compounds with modified functional groups.


2-Chlorobutyryl chloride (CAS 7623-11-2) References

  1. Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications.  |  Iso, Y., et al. 2006. J Med Chem. 49: 1080-100. PMID: 16451073
  2. Synthesis of the Mammea coumarins. Part 2. Experiments in the mammea E series and synthesis of mammea E/AC  |  Leslie Crombie, Raymond C. F. Jones and Christopher J. Palmer . 1987. J. Chem. Soc., Perkin Trans. 1: 333-343.
  3. A synthesis of levetiracetam based on (S)-N-phenylpantolactam as a chiral auxiliary  |  Francesca Boschi a, Pelayo Camps a, Mauro Comes-Franchini b, Diego Muñoz-Torrero a, Alfredo Ricci b, Laura Sánchez a. 2005. Tetrahedron: Asymmetry. 16: 3739-3745.
  4. Iron-modified granular sludge biochar-based catalysts for improved Rhodamine B degradation by activating peroxymonosulfate  |  Bingxing Zhu, Yang Yu, Yindi Ding & Shifu Ge. 2022. Biomass Conversion and Biorefinery.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chlorobutyryl chloride, 5 g

sc-274733
5 g
$247.00